摘要
目的:探讨抗组胺药物在过敏性鼻炎的临床用药情况并分析第一代、第二代抗组胺药物的优缺点及适用范围。方法:筛选过敏性鼻炎确诊患者268例,采用抗组胺药物治疗2周复诊。结果:第二代抗组胺药物(213/268,79.48%)已占主导地位,第一代抗组胺药物的中枢抑制、抗胆碱和胃肠道副作用限制了它的应用(55/268,20.52%);第一代抗组胺药物的中枢抑制、抗胆碱和胃肠道副作用限制了它的应用(55/268,20.52%)。结论:掌握各类各型抗组胺药物的使用,熟悉用药适应证、禁忌证,同时对于过敏性疾病的临床用药规范化、标准化提供参考。
Objective： To investigate the effects of antihistamines in allergic rhinitis, and to analysis the first and second generation antihistamines advantages, disadvantages and applicable scope. Methods：268 patients with allergic rhinitis were recruited, which underwent antihistamines therapy for two weeks then return to clin- ic. Results：The second generation antihistamines had been dominant （213/268, 79.48 % ）, and the side effects of first generation antihistamines limited its application, such as central inhibition, anticholinergic and gastroin-testinal （55/268, 20, 52 % ）. Conclusion： Mastery of tions and contraindications may help allergic rhinitis clinical programmed and standardization of drug. various antihistamines use and familiar treatment, and providing reference for with drug indica- allergic disease at
出处
《内蒙古医学杂志》
2013年第7期823-825,共3页
Inner Mongolia Medical Journal
关键词
过敏性鼻炎
抗组胺药
Allergic rhinitis
Antihistamines
