摘要
目的探讨青年肾细胞癌(肾癌)患者的临床特点、病理类型、诊治方法和预后。方法回顾性分析2004-2011年收治的64例年龄≤40岁的青年肾癌患者的临床资料,总结临床特点和诊治情况。结果男女比为2∶1。所有患者均接受手术治疗,根治性手术46例,保留肾单位术18例。术后临床分期Ⅰ期42例,Ⅱ期12例,Ⅲ期8例,Ⅳ期2例。病理分型分为肾透明细胞癌组47例(73.4%),非透明细胞癌组17例(26.6%)。2组患者的年龄、肿瘤大小、手术方式、临床分期等,差异均有统计学意义(P<0.05)结论青年肾癌早期症状隐匿,易被忽视。病理类型复杂,透明细胞癌组相对预后较好。早期诊断和治疗可改善预后。
Objective To analyze the clinical features and prognosis of renal cell carcinoma（RCC）in adults younger than 40-year-old.Methods The clinical data of 64 cases of renal cell carcinoma patients under 40 years old from 2004 to 2011 were collected.The clinical features,diagnosis and treatment were analyzed.Results The male to female ratio was 2 ∶1（43 ∶21）.All patients underwent surgical treatment,in whom radical surgery for 46 cases,18 cases for nephron-sparing surgery.The postoperative clinical stage was that stageⅠin 42 cases,stageⅡin 12 cases,stage Ⅲ in 8 cases,stage Ⅳ in 2 cases.Postoperative pathology results could be divided into 2 groups： clear cell renal cell carcinoma group in 47 cases（73.4%）,non-clear cell carcinoma in 17 cases（26.6%）.There were significant differences in age,diameter of tumor,operation approach,clinical stages between clear cell renal cell carcinoma group and non-clear cell carcinoma group.Conclusion In young population,RCC is difficult to be diagnosed because of occult symptoms at early stage,so it is easy to be overlooked.The complexity of the pathological type could be observed in this patient population.However,the prognosis of clear cell carcinoma is relatively good.Special attention should be paid to the diagnosis and treatment of young RCC patients.
出处
《北京医学》
CAS
2013年第10期844-846,共3页
Beijing Medical Journal
关键词
肾细胞癌
青年患者
Renal cell carcinoma Young patient
