摘要
慢性鼻-鼻窦炎（CRS）是鼻腔和鼻窦黏膜的慢性炎症，症状持续至少12周，是宿主和环境多因素相互作用的结果。CRS是耳鼻咽喉科的常见疾病，最近有报道指出美国CRS患病率大于16％，
Summary Chronic rhinosinusitis（CRS） is a common disease in otolaryngology, and with the development of the therapy technology, most of the cases have reached a cure. But there are still some intractable cases in clinic, signs and symptoms of chronic rhinosinusitis of which still persist after the standardized drugs and technically adequate endoscopic sinus surgery, and this part is clinically named refractory chronic rhinosinusitis（RCRS）. In re cent studies of the pathogenesis of RCRS, bacterial biofilm（BBF） is attracting more attention. The main emphasis of this review will be to highlight the biological characteristics of BBF, the relationship of BBF and CRS and treatment strategies of BBF positive CRS.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2013年第20期1160-1162,共3页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金
卫生部行业科研专项科研基金资助项目(No:201202005)
关键词
鼻窦炎
细菌生物膜
sinusitis
bacterial biofilm
