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无症状性脑梗死与认知功能障碍关系临床观察 被引量:1

Clinical observation of the relationship between asymptomatic cerebral infarction and cognitive dysfunction
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摘要 目的探讨无症状性脑梗死与认知功能障碍的关系。方法对40例无症状脑梗死患者和40例对照者进行蒙特利尔认知评估量表评估,并分析梗死灶数量、位置等不同因素对认知功能的影响。结果无症状脑梗死患者的认知功能障碍发生率(25%)显著高于对照组(5%,P<0.05);皮质梗死患者的认知功能障碍发病率高于皮质下梗死(P<0.05);多发梗死患者的认知功能障碍发病率高于单病灶患者(P<0.05)。结论无症状性脑梗死可能引起认知功能障碍;皮质及多发病灶患者更易出现认知功能障碍。 Objective Explore the relationship between asymptomatic cerebral infarction and cognitive dysfunction. Methods 40 patients with asymptomatic cerebral infarction patients and 40 controls were assessed Montreal Cognitive Assessment, And analyze infarct number, location and other different factors on cognitive function. Results Asymptomatic cerebral infarction in patients with cognitive dysfunction incidence (25%) was significantly higher Cortical infarction in patients with a high incidence of cognitive dysfunction in subcortical infarcts (P〈0.05); Multi-infarct patients with a high incidence of cognitive dysfunction in patients with single lesions (P〈0.05). Conclusion Asymptomatic cerebral infarction may cause cognitive dysfunction; Patients of cortex and multiple lesions are more vulnerable to have cognitive dysfunction.
出处 《疾病监测与控制》 2013年第10期602-604,共3页 Journal of Diseases Monitor and Control
关键词 无症状性脑梗死 认知功能障碍 蒙特利尔认知评估量表 Asymptomatic cerebral infarction Cognitive dysfunction: Montreal Cognitive Assessment
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  • 1Schneider J A, Boyle P A, Arvanitakis Z, et al.Subcortieal infarcts. Alzheimer's disease pathology, and memory function in older persons[J].Ann Neurol, 2007,62(1):59-66.
  • 2中国防治认知功能障碍专家共识专家组.中国防治认知功能障碍专家共识[J].中华内科杂志,2006,45(2):171-173. 被引量:568
  • 3Nasreddine ZS, Phillips NA, Bedirian V, et al. The Montreal Cognitive Assessment. MoCA:a brief screening tool for mild cognitive in pairment[J].J Am Geriatr Soc, 2005,53(4):695-699.
  • 4VcrmeerSE, LongstrethWT, KoudstaalPJ. Silentbrain infarcts:a sys-tematic review[J].LancetNeuro, 2007,6(7): 611 619.

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