摘要
目的:对直肠癌患者术后发生应激性溃疡出血的相关因素进行探讨,降低应激性溃疡出血的发生率。方法:对我院2008年3月至2012年12月收治的直肠癌手术病例380例患者的临床资料进行回顾性分析,对可能引起术后应激性溃疡出血的因素进行单因素和非条件多因素Logistic分析,探讨引起应激性溃疡出血的独立危险因素。结果:对多种可能引起术后应激性溃疡出血的因素进行单因素分析后发现,年龄超过60岁、超过10年饮酒史、焦虑抑郁状态、淋巴结转移、术后有其他并发症及长时间手术均成为影响应激性溃疡出血的危险因素(P<0.01),有统计学意义。进行多因素Logistic分析后发现,除了超过10年饮酒史外,其余5种因素均可作为直肠癌术后发生应激性溃疡出血的独立危险因素(P<0.01),具有统计学意义。结论:引起直肠癌术后应激性溃疡出血的危险因素较多,临床可依据上述独立危险因素制定可靠的预防措施,以降低术后应激性溃疡出血的发生率。
Objective： To investigate factors related to stress ulcer bleeding in patients with rectal cancer, reduce the incidence of stress ulcer bleeding. Method： 380 cases clinical data of rectal cancer in our hospital from Mar. 2008 to Dec. 2012 were retrospectively analyzed, the factors that may cause stress ulcer hemorrhage after operation were studied with single factor and non conditional Logistic regression analysis, to study the cause of independent risk factors of stress ulcer bleeding. Result： On a variety of factors that may cause stress ulcer hemorrhage after operation of single factor analysis found that, over the age of 60, more than 10 years history of drinking, anxiety and depression, lymph node metastasis, postoperative complica- tions and the other long time operation have become dangerous stress ulcer learn factor { P〈0.01 }, There＇s statistical significance. Multivariate Logistic analysis found that, in addition to more than 10 years history of drinking, the other 5 factors can be used as independent risk factors for postoperative rectal cancer occur- rence of stress ulcer bleeding { P〈0.01 }, with statistical significance. Conclusion： There are many risk factors of stress ulcer bleeding after resection of rectal cancer, clinical basis for the risk of independent factors mentioned above to develop a reliable preventive measures, to reduce the incidence of stress ulcer bleeding after operation.
出处
《河北医学》
CAS
2013年第11期1646-1649,共4页
Hebei Medicine
关键词
直肠癌
应激性溃疡出血
影响因素
Rectal cancer
Stress ulcer bleeding
Influencing factors
