摘要
目的探讨挫伤性视神经病变患者图形视觉诱发电位（P—VEP）振幅下降百分比与客观判断单眼盲的关系。方法回顾性分析31例单眼挫伤性视神经病变病例，将患者按伤眼视力≥0．05与〈0．05分为两组，比较两组间伤眼较对侧健眼P—VEP振幅下降百分比的差异，通过ROC曲线寻找P—VEP振幅下降百分比在两组间的临界值。结果两组患者的P—VEP振幅下降百分比具有统计学显著差异（P〈0．05）。60′方格的P—VEP振幅下降百分比的受试者工作特征曲线（ROC）的曲线下面积（AUC）为0．804，敏感性与特异性最佳点为42．68％，30′方格的AUC为0．719，敏感性及特异性最佳点为67．4％。结论在发生挫伤性视神经病变时，当伤眼较对侧健眼P—VEP振幅下降百分比在60′方格及30′方格中分别达到42．68％与67．4％时，对客观判断单眼盲诊断具有参考价值。
Objective To investigate the predication of unilateral blindness due to contusive optic neuropathy from the percentage of decreased pattern reverse visual evoked potential （P -VEP） amplitude. Methods 31 cases of unilateral contusion optic neuropathy were analyzed retrospectively. They were divided into two groups according to the visual acuity of injuried eye （ ≥ 0. 05 and 〈 0.05 ）. The percentage of decreased P- VEP amplitude was calculated from the difference between the injured eye and contralateral healthy eye. The difference of percentage of decreased P - VEP amplitude between the two groups was statistically analyzed. Receiver operating characteristic curve （ROC） was used to evaluate the cutoff value of two groups. Results The percentages of decreased P - VEP amplitude between two groups were significantly different （ P 〈 0.05 ）. The area under curve （AUC） of ROC curve of the percentage of decreased P - VEP amplitude at 60＇ grid was 0.804, and the cutoff value was 42.68% ; meanwhile, the AUC at 30′ grid was 0. 719, and the cutoff value was 67.4%. Conclusion When the percentage of decreased P - VEP amplitude at 60＇ grid or 30＇ grid in unilateral contusion optic neuropathy is 42.68% or 67.4 % respectively, it is indicated the blindness of injured eye.
出处
《中华眼外伤职业眼病杂志》
2013年第10期731-733,共3页
Chinese Journal of Ocular Trauma and Occupational Eye Disease
基金
基金项目：广东省自然科学基金,（S2012010008732）
关键词
眼挫伤
视神经损伤
视视觉诱发电位
Ocular contusion
Optic neuropathy
Visual evoked potentials
