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正常人紫外线最小红斑量的测定与分析 被引量:1

Determination of minimal erythema dose of normal skin to ultraviolet rays
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摘要 目的 探讨广州地区正常人紫外线最小红斑量(MED)的范围及其与性别、年龄、皮肤光生物学分型、季节和在广州地区生活时间长短的关系.方法 以GS2004型日光紫外模拟系统为光源,测定621例健康志愿者背部正常皮肤的MED值,在照射后(24±2)h由两位经验丰富的观察者同时评定.结果 621例受试者的MED均值为(1170.2±333.2)mJ/cm2,男性MED均值为(1132.8±339.4) mJ/cm2,女性MED均值为(1182.1±330.7) mJ/cm2,两者之间差异无统计学意义(P=0.20);30~50岁年龄组的MED值(1014.7±359.7)mJ/cm2,显著低于20~29岁年龄组(1222.9±304.3) mJ/cm2和50岁以上年龄组(1179.0±374.3) mJ/cm2的MED值(P<0.01);Ⅱ型光生物学皮肤MED值(673.5±228.3) mJ/cm2,显著低于Ⅲ型(1224.3±254.2) mJ/cm2和Ⅳ型皮肤(1363.1±278.5) mJ/cm2的MED值(P<0.01);不同季节测定的MED值差异有统计学意义(P<0.01),春季(969.2±355.8) mJ/cm2最低,夏季(969.24±355.8) mJ/cm2次之,但是秋季与冬季之间则差异无统计学意义(P>0.05);在广州地区生活5~10年组的MED值(1104.9±377.7) mJ/cm2,显著低于1~4年组和10年以上组(P<0.0l).结论 广州地区正常人紫外线MED值范围与中国其他地区正常人MEI)值有一定差异,陈与性别无明显关系外,与年龄、皮肤光生物学分型、季节和在广州地区生活时间长短均有关. Objective To investigate the minimal erythema does (MED) of normal skin to UV in Guangzhou city,and to observe its relationship to sex,age,skin type,seasons and the years lived in Guangzhou.Methods 621 healthy subjects were exposed to Solar Simulator (GS2004) and the MED was measured and observed by two professional technicians after (24±2) hours.Results The average MED value of all subjects was (1170.2±333.2) mJ/cm2.In male and female group,the average MED values were (1132.8-339.4) mJ/cm2 and (1182.1 ± 330.7) mJ/cm2,respectively,and there was no significant difference between male and female (P=0.20).The MED value in subjects aged from 30 to 50 (1014.7 ± 359.7) mJ/cm2 was significantly lower than those aged from 20 to 29 (1222.9±304.3) mJ/cm2 and over 50 years (1179.0±374.3) mJ/cm2 (P〈0.01).The MED value in skin type Ⅱ (673.53±228.3) mJ/cm2 was significantly lower than those in type Ⅲ (1224.3±254.2) mJ/cm2 and Ⅳ(1363.1±278.5) mJ/cm2(P〈0.01).There was significant difference of the MED value between different seasons (P〈0.01).The MED value in spring (969.2±355.8) mJ/cm2 was lowest,and followed by summer (969.2± 355.8) mJ/cm2.However,there was no significant difference between autumn and winter (P〉0.05).The MED value in subjects lived in Guangzhou from 5 to 10 years was significantly lower than those whose residence time was from 1 to 4 years and over 10 years,respectively.Conclusions The MED value of the subjects in Guangzhou is quite different from other cities of China,and related to age,skin types,seasons and the years lived in Guangzhou city,while there is no correlation between MED value and gender difference.
出处 《中华医学美学美容杂志》 2013年第5期365-367,共3页 Chinese Journal of Medical Aesthetics and Cosmetology
关键词 最小红斑量 紫外线 Minimal erythema dose (MED) Ultraviolet (UV)
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