期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

颅脑冲击波损伤离体细胞模型研究进展 被引量：1

下载PDF
导出
摘要 近年来,颅脑冲击波损伤不断增多。研究显示致肺损伤阈值下的冲击波能导致急性和延迟性的行为缺陷和神经变性[1]。因此,冲击波导致的颅脑损伤比肺冲击伤的损害更常见,危害也更大。冲击波损伤常给患者遗留多种神经功能障碍,轻者影响正常生活和工作,重者生活不能自理、植物生存甚至死亡,具有高致残率、高死亡率的特点[2]。因此,冲击波导致颅脑损伤的研究是神经外科领域的一个热点。
作者 李怀东 郭少华
机构地区 解放军第 解放军第
出处 《中国临床神经外科杂志》 2013年第9期573-575,共3页 Chinese Journal of Clinical Neurosurgery
关键词 颅脑损伤 冲击波 离体细胞模型 进展
分类号 R642 [医药卫生—外科学]
  • 相关文献

参考文献19

  • 1Rafaels KA, Bass CR, Panzer MB, et al. Pulmonary injury risk assessment for long-duration blasts: a meta-analysis [J]. J Trauma, 2010, 69(2): 368-374.
  • 2McCarthy M, Dikmen S, Langlois L, et al. Self-reported psychosocial health among adults with traumatic brain injury [J]. Arch Phys Med Rehabil, 2006, 87(7): 953-961.
  • 3Chen YC, Smith DH, Meaney DF. In-vitro approaches for studying blast-induced traumatic brain injury [J]. J Neuro- trauma, 2009, 26(6): 861-876.
  • 4Siesjo BK. Basic mechanisms of traumatic brain damage [J]. Ann Emerg Med, 1993, 22(3): 959-969.
  • 5LaPlaea MC, Thibauh LE. An in vitro traumatic injury model to examine the response of neurons to a hydrodynamically- induced deformation [J]. Ann Biomed Eng, 1997, 25(4): 665-677. M.
  • 6orrison B 3rd, Elkin BS, Dolle JP, et al. In vitro models of traumatic brain injury [J]. Annu Rev Biomed Eng, 2010, 13 (8): 91-126.
  • 7Arun P, Spadaro J, John J, et al. Studies on blast traumatic brain injury using in-vitro model with shock tube [J]. Neu- roreport, 2011, 22(8): 379-384.
  • 8Effgen GB, Hue CD, Vogel E 3rd, et al. A multiscale app- roach to blast neurotrauma modeling: part 11 : methodology for inducing blast injury to in vitro models [J]. Front Neurol, 2012, 3(2): 1-10.
  • 9Skotak M, Wang F, Chandra N. An in vitro injury model for SH-SY5Y neuroblastoma cells: effect of strain and strain rate [J]. J Neurosci Meth, 2012, 205(1):159-168.
  • 10Nishimura N, Schaffer CB, Friedman B, et al. Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke [J]. Nat Meth, 2006, 3 (2): 99-108.

二级参考文献18

  • 1[1]Tavalin SJ, Ellis EF, Satin LS. Inhibition of the electrogenic Na pump underlies delayed depolarization of cortical neurons after mechanical injury or glutamate [J]. J Neurophysiol, 1997; 77(2): 632-638.
  • 2[2]Bleiberg J, Kane RL, Reeves DL, Garmoe WS, Halpern E. Factor analysis of computerized and traditional tests used in mild brain injury research [J]. Clin Neuropsychol, 2000;14(3):287-294.
  • 3[3]Lee VM, Thibault LE. An in vitro model of traumatic neuronal injury: Loading rate-dependent changes in acute cytosolic calcium and lactate dehydrogenase release [J]. J Neurotrauma, 1997;14(6): 355-368.
  • 4[4]Movsesyan VA, O'Leary DM, Fan L, Bao W, Mullins PG, Knoblach SM, Faden AI. mGluR5 antagonists 2-methyl-6-(pheny-lethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors [J]. J Pharmacol Exp Ther, 2001;296(1):41-47.
  • 5[5]Ostrow LW, Langan TJ, Sachs F. Stretch-induced endothelin-1 production by astrocytes [J]. J Cardiovasc Pharmacol, 2000;36(5 Suppl 1):S274-S277.
  • 6[6]Nakayama Y, Aoki Y. Mechanism responsible for the formation of focal swellings on injured neuronal processes using a novel in vitro model of axonal injury [J]. Forensic Sci Int, 2000;113(1-3):245-249.
  • 7[7]Situ ZQ, Wu JZ. Xibao Peiyang (Cell culture) [M]. Xi'an: Shijie Tushu Chuban Gongsi (World Publishing Corporation), 1996:121-125.
  • 8[8]Ellis EF, Mckinney JS, Willoughby KA, Liang S, Povlishock JT. A new model for rapid stretch-induced injury of cells in culture: Characterization of the model using astrocytes [J]. J Neurotrauma, 1995;12(3):325-339.
  • 9[9]Jones KH, Senft AJ. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propi-dium iodide [J]. J Histochem Cytochem, 1985;33:77-79.
  • 10[10]Murphy EJ, Horrocks LA. A model for compression trauma: Pressure-induced injury in cell cultures [J]. J Neurotrauma, 1993;10(4):431-444.

共引文献9

同被引文献8

引证文献1

二级引证文献1

中国临床神经外科杂志
2013年 第9期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部