摘要
目的:探讨新生儿母乳性黄疸阴阳属性转化的影响因素。方法:对68例确诊母乳性黄疸病例进行回顾性分析并追踪随访,第3至8周每周至少随访1次。记录患儿日龄、性别、胎龄、出生体质量、分娩方式、出生时窒息史、精神状态、皮肤颜色、每日喂奶次数、有无呕吐、大便情况、黄疸出现时间、经皮测胆红素值、口服退黄药物情况及黄疸消退时间等。化验血常规及肝功能指标。其中22例病程中曾由阳黄转化为阴黄。对此22例患儿(观察组)及其他患儿(对照组)临床资料进行统计。应用PEMS 3.1 For Windows统计软件进行分析。结果:观察组每日母乳喂养的次数(7.8±0.5 vs 8.2±0.7)、口服茵栀黄的天数(14.7±3.1 vs 12.6±2.9)及化验ALP、GGT值与对照组有不同,差异均有统计学意义(P<0.05)。黄疸消退时间较对照组延长(57.1±5.7 vs 52.9±6.2),差异有统计学意义(P<0.05)。结论:新生儿母乳性黄疸的阴阳属性可相互转化,其发生与多因素有关。不恰当服用寒凉药物、较高的血清ALP、GGT值可促进阳黄向阴黄转化,增加喂奶次数则通过促进黄疸消退而减少其转化。
Objective： To investigate the factors correlative with Yin and Yang jaundice syndrome transformation in neonates with breast milk jaundice. Methods： 68 cases of neonates with breast milk jaundice were retrospectively analyzed and followed-up at least once a week from the third to eighth week after birth. The data collected for the neonates was age, sex, natal age, birth weight, mood of delivery, history of asphyxia, time for skin jaundice occurrence and disappearance, state of vomiting, feces and breast feeding. Blood routine and hepatic functions were tested for every neonate. Among of them, 22 cases with Yang jaundice syndrome once transformed to Yin jaundice syndrome （ test group ）. Others were as control group. The data was analyzed by PEMS 3.1 for Windows statistic software. Results： In test group, times of feeding （ 7.8 ± 0.5 vs 8.2_± 0.7 ）, days having Yinzhihuang oral liquor[ （ 14.7 ± 3.1 ） d vs （12.6 ± 2.9）d], and ALP and GGT levels were different from that of neonates in control group. The difference was statistically significant （P〈0.05）. Disappeared time of jaundice in skin[ （ 57.1-± 5.7 ）d vs （52.9 ± 6.2 ）d] in the two groups also had statistically difference （ P〈0.05 ）. Conclusion ： Yin and Yang jaundice syndromes can transform to each other. Inappropriate use of Yinzhihhuang oral liquor, high ALP and GGT levels can promote the transformation, while increasing feeding times may reduce the transformation by promoting jaundice disappearance.
出处
《辽宁中医药大学学报》
CAS
2013年第11期198-200,共3页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
母乳性黄疸
阴黄
阳黄
影响因素
breast milk jaundice
Yin jaundice syndrome
Yang jaundice syndrome
correlative factor 2
