摘要
目的观察五子衍宗汤加味配合电针治疗老年功能性尿失禁的临床疗效。方法将老年功能性尿失禁患者113例随机分成治疗组65例和对照组48例,对照组给予五子衍宗汤加味,每日1剂分2次服;治疗组在此基础上加用电针治疗,每日1次。两组均连续治疗4周后评价临床疗效,观察两组治疗前和治疗2周、4周及2个月随访时尿失禁症状,包括日平均排尿次数、夜平均因小便起床次数、日平均尿失禁次数、夜平均尿床次数、尿失禁积分,并观察不良反应。结果治疗组治疗2周、4周及随访时各项症状积分与治疗前比较,差异均有统计学意义(P<0.05);除日平均排尿次数外,其他各项症状积分治疗4周、随访时与治疗2周积分比较,差异均有统计学意义(P<0.05)。对照组治疗2周尿失禁积分与治疗前比较差异有统计学意义(P<0.05),其他各项症状积分差异均无统计学意义(P>0.05);治疗4周、随访时各项症状积分与治疗前比较差异有统计学意义(P<0.05)。对照组治疗4周后、随访时各项症状积分与治疗组同时间比较,差异均有统计学意义(P<0.05)。治疗组临床疗效总有效率、随访复发率、疗效巩固率分别为92.3%、15.0%、85.0%,对照组分别为64.6%、45.2%、54.8%,两组比较差异均有统计学意义(P<0.05)。结论加味五子衍宗汤联合电针治疗老年功能性尿失禁可明显改善患者临床症状,不良反应少,且临床疗效优于单纯口服五子衍宗汤加味治疗。
Objective To compare the therapeutic effect of supplemented Wuzi Yanzong Decoction （Five-Seed Progeny Decoction） combined with electroacupuncture （EA） and simple oral decoction for urinary incontinence （UI） in the elderly. Methods Totally 113 elderly patients with UI were randomized into treatment group of 65 cases and control group of 48 cases. The control group was given supplemented Wuzi Yanzong Decoction one dose daily. The treatment group was added with EA, once per day. The treatment lasted for 4 weeks. The clinical efficacy was evaluated. The average numbers of nocturia, daily UI and night bedwetting and UI scores were observed before treatment, in the 2nd week and 4th week of treatment and in the 2nd month of follow-up. The adverse reactions were observed. Results There were significant differences between before treatment and after 2-week treatment, 4-week treatment and 2-month follow-up in indicator scores in the treatment group （P〈0.05 or P〈0.01）, especially after 4-week treatment and 2-month follow-up as compared with after 2-week treatment except the average frequency of daily urination （P〈0.05 or P〈0.01）. There was a significant difference between before treatment and after 2-week treatment in the UI score in the control group （P〈0.05）. There were significant differences between before treatment and after 4-week treatment and 2-month follow-up in indicator scores in both groups （P〈0.05）, especially in the treatment group （P〈0.05）. The total effective rate, recurrence rate and consolidation rate was 92.3%, 15% and 85.0% in the treatment group and 64.6%, 45.20% and 54.8% in the control group respectively, with a significant difference between groups （P〈0.05）. Conclusion Supplemented Wuzi Yanzong Decoction combined with EA can obviously relieve the symptoms of elderly patients with UI with fewer adverse reactions and a better efficacy as compared with simple herbal treatment.
出处
《中医杂志》
CSCD
北大核心
2013年第21期1843-1846,共4页
Journal of Traditional Chinese Medicine
关键词
五子衍宗汤加味
电针
老年功能性尿失禁
supplemented Wuzi Yanzong Decoction （Five-Seed Progeny Decoction）
electroacupuncture
urinary incontinence inthe elderly
