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儿童消化性溃疡小肠细菌过度生长情况研究 被引量:1

A Study on small intestinal bacterial overgrowth in children peptic ulcer
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摘要 目的探讨儿童消化性溃疡(PU)患者小肠细菌过度生长(SIBO)的情况,以及SIBO与其幽门螺杆菌(HP)感染之间的关系。方法对30例儿童PU患者按HP感染情况分为HP阳性组(22例)、HP阴性组(8例)两组,通过葡萄糖氢呼吸试验(GHBT)分别检测其SIBO情况,并与健康对照组进行组间比较。结果 30例儿童PU患者,HP阳性组和HP阴性组患儿与健康对照组的SIBO阳性率及试餐后呼气氢浓度比较差异均有统计学意义(P<0.01);儿童PU患者HP阳性组与HP阴性组SIBO阳性率及试餐后呼气氢浓度比较差异也有显著统计学意义(P<0.01)。结论儿童消化性溃疡SIBO发生率高,若合并HP感染,其SIBO发生率增加尤为显著,推测儿童消化性溃疡SIBO阳性率高与幽门螺杆菌存在某种关联。 Objective To investigate the conditions of small intestinal bacterial overgrowth ( SIBO ) in children with peptic ulcer ( PU), as well as its correlation with helicobaeter pylori (HP) infection. Methods Thirty children with PU were divided into HP positive group (n = 22) and negative group (n = 8). Their SIBO were detected by glucose hydrogen breath test (GHBT) and com- pared with that of healthy control group. Results There were significant differences in positive rate of SIBO and in breath hydrogen concentration after a meal between any of the two child groups and the control group (P 〈 0. 01 ). Between the two child groups, there were also significant differences in the above parameters ( P 〈 0.01 ). Conclusion In the children with PU, the incidence of SIBO is high. In addition to HP infection, it increases significantly. We speculate that there is a certain relationship between high positive rate of SIBO and HP in children with PU.
机构地区 解放军第
出处 《临床军医杂志》 CAS 2013年第10期1013-1014,共2页 Clinical Journal of Medical Officers
关键词 消化性溃疡 儿童 幽门螺杆菌 小肠细菌过度生长 葡萄糖氢呼气试验 peptic ulcer child helicobacter pylori small intestinal bacterial overgrowth glucose hydrogen breath test
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