期刊文献+

二甲双胍与甲状腺疾病 被引量:11

原文传递
导出
摘要 作为一种传统的口服降糖药,二甲双胍已应用于临床半个多世纪。近年来,有关二甲双胍与甲状腺疾病间联系的研究成为焦点。糖尿病患者常伴有甲状腺功能异常或甲状腺结节,二甲双胍治疗可引起甲状腺功能改变,并使甲状腺结节的体积变小。这一现象引起了诸多学者的注意,这类药物在甲状腺疾病治疗中的地位和作用值得进一步探讨。
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2013年第10期I0002-I0005,共4页 Chinese Journal of Endocrinology and Metabolism
基金 国家自然科学基金资助项目(81200577) 江苏省科技计划项目(BM2012064)
  • 相关文献

参考文献1

二级参考文献22

  • 1Araujo RL.Andrade BM,Padron AS,el al.High-fat diet increases thyrotropin and oxygen consumption without altering circulating 3,5,3'-triiodothyronine (T3) and thyroxine in rats:The role of iodothyro-nine deiodinases,reverse T3 production,and whole-body fat oxidation.Endocrinology,2010,[Epub ahead of print] .
  • 2Moulin de Moraes CM.Mancini MC,de Melo ME,et al.Prevalence of subclinical hypothyroidism in a morbidly obese population and improvement after weight loss induced by Roux-en-Y gastric bypass.Obes Surg,2005,15:1287-1291.
  • 3Grandone A,Santoro N.Coppola F,et al.Thyroid function derangement and childhood obesity-An Italian experience.BMC En-docr Disord,2010,10:8.
  • 4Rotondi M,Leporati P,La Manna A,et al.Raised serum TSH levels in patients with morbid obesity:Is it enough to diagnose sub-clinical hypothyroidism? Eur J Endocrinol,2009,160:403-408.
  • 5Knudsen N,Laurberg P,Rasmussen LB,et al.Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population.J Clin Endocrinol Metab,2005,90:4019-4024.
  • 6Ortega E,Pannacciulli N,Bogardus C,et al.Plasma concentrations of free triiodothyronine predict weight change in euthyroidpersons.Am J Clin Nutr,2007,85:440-445.
  • 7Ambrosi B,Masserini B.Iorio L,et al.Relationship of thyroid function with body mass index and insulin-resistance in euthyroid obese subjects.J Endocrinol Invest,2010,[Epub ahead of print] .
  • 8Araujo RL.Andrade BM.da Silva ML,et al.Tissue-specific deio-dina.se regulation during food restriction and low replacement dose of leptin in rats.Am J Physiol Endocrinol Metab,2009,296:1157-1163.
  • 9Shaikh MG.Grundy RG.Kirk JM.Hyperleptinaemia rather than fasting hyperinsulinaemia is associated with obesity following hy-pothalamic damage in children.Eur J Endocrinol,2008,159:791-797.
  • 10Kok P.Roelfsema F,Frolich M,et al.Spontaneous diurnal thyrotropin secretion is enhanced in proportion to circulating leptin in obese premenopausal women.J Clin Endocrinol Metab,2005,90:6185-6191.

共引文献8

同被引文献89

  • 1彭玉兰,罗燕,张卫东,冯超,赵丽华,陈运.老年人甲状腺结节及甲状腺功能的相关性探讨[J].中华老年医学杂志,2005,24(4):290-291. 被引量:22
  • 2张宏,方佩华,郑凝,常宝成,赵伟,董如娇,王家驰.住院2型糖尿病患者甲状腺功能状态的分析[J].国际内分泌代谢杂志,2007,27(2):139-141. 被引量:79
  • 3李清亚,张松,祝扬,王晓慧,毛忠强,宋瑞华,程永虎.不同年龄及性别国人体脂和总体水分含量的测量分析[J].解放军预防医学杂志,2007,25(6):412-415. 被引量:13
  • 4Cappelli C, Rotondi M, Pimla I, et al. TSH-Iowering effect of metformin in type 2 diabetic patients: differences between euthyroid, untreated hypothyroid, and euthyroid on L-T4 therapy patients. Diabetes Care, 2009, 32(9):1589-1590.
  • 5Vondra K, Vrbikova J, Dvorakova K. Thyroid gland disea- ses in adult patients with diabetes mellitus [ J ]. Minerva Endocrinol, 2005, 30(4):217-236.
  • 6Tamez - Prez HE, Martnez E, Quintanilla - Flores DL, et al. The rate of primary hypothyroidism in diabetic patients is greater than in the non - diabetic population. An obser- vational study [ J ]. Med Clin,2012, 138 ( 11 ) :475 - 477.
  • 7Rezz6nico J, Rezz6nico M, Pusiol E, et al. Metforim treat- ment for small benign thyroid nodules in patients with insu- lin resistance [ J]. Metab Syndr Relat Disord, 2011, 9 (1) :69 -75.
  • 8Reaven GM. Role of insulin resistance in human disease [J]. Diabetes, 1988, 37(12) :1595 - 1607.
  • 9Ittermann T, Markus MR, Schipf S, et al. Metforalin in- hibits goitrogenous effect of type 2 diabetes [ J ]. Eur J En- docrinol,2013,169( 1 ) :9 - 15.
  • 10Bowker SL, Majumdar SR, Veugelers P, et al. Increased cancer related mortality forpatients with type 2 diabetes who use sulfonylureas or insulin: Response to Farooki and Schneider[ J ]. Diabetes Care, 2006, 29 (8) : 1990 - 1991.

引证文献11

二级引证文献49

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部