期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

男男性行为人群艾滋病暴露前预防用药相关情况分析 被引量：12

Awareness,experience and willingness of using HIV pre-exposure prophylaxis among men who have sex with men
原文传递
导出
摘要 目的了解男男性行为者(men who have sex with men,MSM)人群对艾滋病暴露前预防用药(pre-exposure prophylaxis,PrEP)的知晓情况、使用经历、使用意愿及其预测因子。方法采用结构式自填定量问卷对中国西部重庆、四川和广西3省招募的1 407名MSM进行调查。获得1 402份有效问卷,采用单变量描述性统计分析方法描述PrEP知晓情况、使用经历、使用意愿;利用单因素和多因素Logistic回归分析探讨PrEP使用意愿的预测因子。结果 22.1%(95%CI:20.0%～24.3%)的调查对象报告先前听说过PrEP,没有证据显示有人真正使用过PrEP。在PrEP安全、有效的条件下,63.6%(95%CI:61.0%～66.1%)的调查对象表示非常愿意使用。使用意愿的主要预测因子为:较低的文化程度、中等收入相对于低收入、最近6个月从不或很少从网上寻找性伴、有性病史、较高的艾滋病知识知晓、担心艾滋病对自己和家人造成威胁、先前听说过PrEP以及认为PrEP预防HIV感染有效。结论 MSM人群PrEP知晓率较低,一旦PrEP的安全性和有效性得到证实,MSM人群有较高的PrEP使用意愿,在MSM人群中推广PrEP具有较高的可行性。 Objective To investigate the awareness, experience and willingness of using HIV pre-exposure prophylaxis （PrEP） among men who have sex with men （MSM）, and to study the predictors of the willingness to use PrEP. Methods A total of 1 407 MSM were recruited from Chongqing, Sichuan, and Guangxi to complete an anonymous, structural quantitative survey, with 1 402 qualified questionnaires analyzed. Descriptive analysis was conducted for the awareness, experience and willingness of using PrEP. Predictors of willingness to use PrEP were analyzed by logistic regression. Results Of all the participants, 22.1% （95%CI： 20.0% to 24.3%） reported that they had previously heard of PrEP. No participant reported definite PrEP use. The results indicated that 63.6% （95%CI： 61.0% to 66.1%） of participants were willing to use PrEP in the future if it was proven safe and effective. The predictors of willingness to use PrEP included lower education, moderate income compared with the lowest income, never or rarely finding sex partners on the Internet, sexually transmitted infection （STI） history, more knowledge of AIDS, being worried about HIV as a threat to themselves and their family, hearing about PrEP previously, and perception of PrEP efficacy. Conclusion The awareness of PrEP among MSM in Western China is modest, but the high interest in using PrEP suggests that implementing and promoting PrEP in this population is feasible.
作者 张燕 钟晓妮 彭斌 梁浩 彭鸿斌 黄爱龙
机构地区 重庆医科大学公共卫生与管理学院卫生统计学教研室 广西医科大学公共卫生学院流行病与卫生统计学教研室 南充市顺庆区疾病预防控制中心 重庆医科大学感染性疾病分子生物学教育部重点实验室
出处 《第三军医大学学报》 CAS CSCD 北大核心 2013年第20期2226-2230,共5页 Journal of Third Military Medical University
基金 国家科技重大专项(2008ZX10001-016)~~
关键词 艾滋病 暴露前预防用药 男男性行为者 使用意愿 human immunodeficiency virus pre-exposure prophylaxis men who have sex with men willingness of use
分类号 R183.7 [医药卫生—流行病学] R195.4 [医药卫生—卫生统计学]
  • 相关文献

参考文献17

  • 1中华人民共和国卫生部,联合国艾滋病规划署,世界卫生组织.2011年中国艾滋病疫情估计报告[R].北京:中华人民共和国卫生部,联合国艾滋病规划署,世界卫生组织,2011.
  • 2SheltonJ D, Halperin D T, Wilson D. Has global HIV incidence peaked?[J]. Lancet, 2006, 367 (9517): 1120 -1122.
  • 3AVAC. Pre-exposure prophylaxis (PrEP)[OLJ.[2013-03-27J. ht?tp: Ilwww. avac. orglhti dI spl alGetDocumentActionii/5851.
  • 4Denton P W, EstesJ D, Sun Z, et af. Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV -1 in humanized BLT mice[J]. PLoS Med, 2008, 5(1): e16.
  • 5Van-Rompay K K A, McChesney M B, Aguirre N L, et al. Two low doses of tenofovir protect newborn macaques against oral simian immu?nodeficiency virus infection[J].J Infect Dis, 2001, 184(4): 429 - 438.
  • 6Garcia-LermaJ G, Otten R A, Qari S H, et al. Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovirj I}. PLoS Med, 2008, 5(2): e28.
  • 7Grant R M, LamaJ R, Anderson P L, et al, Preexposure chemopro?phylaxis for HIV prevention in men who have sex with men[J]. N EnglJ Med, 2010, 363(27): 2587 -2599.
  • 8BaetenJ M, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women[J]. N EnglJ Med, 2012,367(5): 399 -410.
  • 9Thigpen M C, Kebaabetswe PM, Paxton LA, et af. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana[J]. N EnglJ Med, 2012, 367 (5) : 423 -434.
  • 10AVAC. Ongoing PrEP trial[OLJ.[2013-03-27J http://data. avac. orgiOngoingPrEPTrials. aspx.

共引文献16

同被引文献118

  • 1中华人民共和国卫生部,联合国艾滋病规划署,世界卫生组织.2011年中国艾滋病疫情估计.2011.
  • 2AVAC. Pro-exposure prophylaxis (PREP) [ OL]. [ 2013-09-27 ]. ht- tp ://www. avac. org/ht/d/sp/a/GetDocumentAction/i/5851.
  • 3Denton P W, Estes J D, Sun Z, et al. Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice[J]. PLoSMed, 2008, 5(1): el6.
  • 4Van-Rompay K K, McChesney M B, Aguirre N L, et al. Two low do- ses of tenofovir protect newborn macaques against oral simian immunod- eficiency virus infection[J]. J Infect Dis, 2001, 184(4) : 429 -438.
  • 5Garcia-Lerma J G, Otten R A, Qari S H, et al. Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir[ J]. PLoS Med, 2008, 5 (2) : e28.
  • 6Grant R M, Lama J R, Anderson P L, et al. Preexposure chemopro- phylaxis for HIV prevention in men who have sex with men[ J]. N Engl J Med, 2010, 363(27) : 2587 -2599.
  • 7Baeten J M, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women[J].N Engl J Med, 2012, 367(5) : 399 -410.
  • 8Thigpen M C, Kebaabetswe P M, Paxton L A, et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana [J]. N Engl J Med, 2012, 367(5) : 423 -434.
  • 9Weeks M R, Mosack K E, Abbott M, et al. Microbicide acceptability among high-risk urban U. S. women: experiences and perceptions of sexually transmitted HIV prevention [ J ]. Sex Transm Dis, 2004, 31 ( 11 ) : 682 - 690.
  • 10Newman P A, Duan N, Lee S J, et al. HIV vaccine acceptability among communities at risk: the impact of vaccine characteristics[J]. Vaccine, 2006, 24 (12) : 2094 - 2101.

引证文献12

二级引证文献67

第三军医大学学报
2013年 第20期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部