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支撑喉镜下CO_2激光微创手术治疗早期喉癌的疗效分析 被引量:7

Eicacy of transoral CO_2laser microsurgery for early laryngeal cancer
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摘要 【摘要】目的:探讨CO2激光微创手术治疗早期喉癌的疗效。方法:回顾性分析2003年4月-2008年4月接受CO2激光微创手术治疗的186例早期喉癌患者的临床资料,分析术后近期疗效和远期结局。结果:186例TisN0M0~T3N0M0期声门型及声门上型喉癌患者的3年总生存率为96.3%,局部控制率为87.7%,局部复发率为3.7%;5年总生存率为92.0%,局部控制率为77.8%,局部复发率为22.6%;淋巴结转移率为9.1%。结论: CO2激光微创手术治疗早期声门型及声门上型喉癌的近期疗效和远期结局均较好,并可保留喉功能;而在中晚期喉癌和声门上型喉癌患者中应慎重选择CO2激光微创手术。 Objective: To explore the efficacy of transoral CO2 laser microsurgery in patients with early laryngeal carcinoma. Methods: Total of 186 patients with stages TisNoMo-T3NoMo glottic or supraglottic laryngeal cancer between April 2003 and April 2008 were retrospectively collected. All of these patients received CO2 laser microsurgery. The clinical records and the follow-up information were analyzed. Results: The overall 3-year survival rate was 96.3%, 3-year local control rate was 87.7%, and 5-year local recurrence rate was 3.7%; the overall 5-year survival rate was 92.0%, 3-year local control rate was 77.8%, and 5-year local recurrence rate was 22.6%; the rate of lymph node metastasis was 9.1%. Conclusion: As the first choice for T1_2 glottic and supraglottic laryngeal cancer, transoral COz laser microsurgery can excise tumor correctly with the larynx being preserved, having a good long-term outcome. However, for advanced laryngeal cancer and supraglottic laryngeal cancer, transoral CO2 laser microsurgery should be carefully considered.
出处 《肿瘤》 CAS CSCD 北大核心 2013年第10期909-913,共5页 Tumor
基金 江西省自然科学基金资助项目(编号:20114BAB205069)
关键词 喉癌 早期 CO2激光微创手术 治疗结果 Laryngeal cancer Early stage COz laser microsurgery Treatment outcome
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参考文献12

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二级参考文献24

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