摘要
目的研究多种肿瘤标记物联合检测在肺癌诊断及鉴别诊断中的意义,并寻找可靠的具有组织学特异性的肺癌肿瘤标记物,以指导肺癌组织学分型以及治疗方案的选择。方法采用电化学发光免疫法(ECLIA),对112例肺癌患者、82例肺部良性病变患者、90例健康查体人员进行CYFRA21-1、SccAg、NSE、CEA检测。结果肺癌患者血清中4种肿瘤标记物水平均明显高于肺部良性病变组及对照组,CYFRA21-1及SccAg在鳞癌患者中水平最高,NSE在小细胞肺癌患者中水平最高,CEA在腺癌患者中水平最高。结论多种肿瘤标记物联合检测有助于肺癌的诊断,并能指导临床进行肺癌组织学分型以及选择最佳的治疗方案。
Objective diagnosis and it＇s differential reliable histological specificity Methods By using electroche To study the significance of combined detection of tumor marks in lung cancer diagnosis; Moreover to look for the tumor marker of lung cancer which have a so as to guide the histological typing of lung cancer and its treatment programs. nce immunoassay（ECLIA） the detection of CYFRA21-1, SccAg, NSE, and CEA was taken among the participants which included 112 patients with lung cancer, 82 with benign lung disease and 90 health persons. Results Four tumor marks in the serum of patients with lung cancer were significantly higher than benign lung disease group and control group, CYFRA21-1 and SccAg were at the highest level in patients with squamous cell carcinoma, NSE was at the highest level in small cell lung cancer patients, and CEA was at the highest level in patients with adenocarcinoma. Conclusion The combined detection of multiple tumor marks contributes the diagnosis of lung cancer significantly. It can also help to guide the clinical histological typing of lung cancer and choose the best treatment programs.
出处
《实用医药杂志》
2013年第10期880-882,共3页
Practical Journal of Medicine & Pharmacy
