摘要
目的 观察地佐辛在妇科腹腔镜手术不同时间点应用对患者苏醒时间的影响.方法 择期妇科腹腔镜手术患者60例,ASAⅠ~Ⅱ级,随机分为3组,每组20例.术中静吸复合麻醉,A组在气管插管后给予地佐辛0.1 mg/kg;B组于关闭气腹时给予地佐辛0.1 mg/kg;C组给予生理盐水.记录三组患者手术结束后的血压（MAP）、心率（HR）和呼吸（RR）的变化,术后5 min的VAS评分、苏醒时间、改良OAA/S评分.结果 B组各项生命体征平稳状态优于其他两组,患者苏醒时间较其他两组延长（P〈0.05）;术后5 min的VAS评分A、B组比较差异无统计学意义（P〉0.05）;A、B组VAS评分低于C组（P〈0.05）;A组改良OAA/S评分高于B组（P〈0.05）.结论 手术近结束时给予地佐辛可延长患者的苏醒时间和苏醒质量,建议地佐辛在全身麻醉中镇痛时尽量早期使用.
Objective To observe the effect on recovery from general anesthesia in patients with gynecological laparoscopic surgery by dezocine at different time points. Methods 60 patients with elective gynecological laparoscopic surgery of ASA Ⅰ - Ⅱwere randomly divided into 3 groups. Intraoperative intravenous inhalation anesthesia were given. Group A：symplectic 0. 1 mg/kg after endotracheal intubation;group B ：0. 1 mg/kg with closing pneumoperitoneurn ; group C ： physiological saline. The blood pressure （MAP） , heart rate （HR） , respiratory rate （RR） were observed, the VAS score,recovery time,improved OAA/S score at 5 min after operation were recorded. Results The vital signs in group B was better than those of the other groups （ P 〈 0. 05 ） ; the recovery time in group B was longer than those of the other groups（ P 〈0. 05 ）. There was no significant difference in VAS score at 5 min after operation between group A and group B （ P 〉 0. 05 ） ; the VAS score in group A and group B was lower than that of group C （ P 〈 0. 05 ）. The improved OAA/S score in group A was higher than that of group B （ P 〈 0. 05 ）. Conclusion It could extend the recovery time and quality with dezocine at the end of the surgery, and the dezocine can be used as early as possible in the analgesia of general anesthesia.
出处
《实用药物与临床》
CAS
2013年第10期911-912,共2页
Practical Pharmacy and Clinical Remedies
关键词
地佐辛
妇科腹腔镜手术
苏醒时间
Dezocine
Gynecologic laparoscopic surgery
Recovery time
