摘要
原发性肝癌是世界性常见的恶性肿瘤之一，肝癌的早发现早治疗已成为临床研究的重点。射频消融术（RFA）在国内外已成为公认的对小肝癌治疗有效的一种手段，尤其对于直径小于3CIB的小肝癌患者，治愈率已经达到甚至超过外科切除治疗。在治疗直径大于3cm的小肝癌患者，单一的RFA治疗复发率相对较高。肝动脉化疗栓塞（TACE）对小肝癌的治疗效果早已获得承认，但也存在一定的缺点。TACE术后改变了原有的动脉供血系统，侧支循环容易建立，病灶坏死率较低，复发率较高，多次TACE治疗会加重肝功能的损害。TACE与RAF联合能在小肝癌患者治疗中取长补短，提高治疗的安全性、有效性，以及对患者的远期疗效。本文主要对肝动脉化疗栓塞术联合射频消融术治疗小肝癌的现状及其进展做一综述。
Primary liver cancer is a common malignancy worldwide. Early detection and early treatment of liver cancer has become the focus of clinical research. Radiot^requency ablation（RFA） at home and abroad has been recognized as an effective treatment for small hepatocellular carcinoma, especially for the small diameter of less than 3 cm in patients with liver cancer. The cure rate has reached or even exceeded surgical resection. Diame- ter greater than 3 cm in the treatment of small hepatocellutar carcinoma in patients treated with RFA single recur- rence rate is relatively high. Transcatheter ＇arterial ehemoembolization （TACE） for the treatment of liver cancer has long been recognized, but there are also some disadvantages. After TACE, the original artery system is changed, easy to set up collateral circulation, focal necrosis rate is low, the recurrence rate is high, and repeated TACE treatment will increase the liver function damage. TACE combined with the RAF in the treatment of small hepatocellular carcinoma in patients with each other, improve treatment safety, efficacy, and long - term outcome for patients. This paper studies the TACE combined RFA of small hepatoeellular carcinoma status and progress.
出处
《实用肿瘤学杂志》
CAS
2013年第5期447-451,共5页
Practical Oncology Journal
基金
卫生部医药卫生科技发展研究项目（W2011BX087）
