摘要
目的探讨血脂代谢和尿蛋白在子痫前期疾病中的关系及其意义。方法选择妊娠晚期的41例子痫前期孕妇和36名健康孕妇为研究对象,检测其血清甘油三酯、总胆固醇、LDL-C、HDL-C和极低密度脂蛋白胆固醇(VLDL-C)以及尿蛋白定量,分析血脂代谢与蛋白尿严重程度间的关系。结果尿蛋白重度升高的子痫前期孕妇的VLDL-C和甘油三脂水平均明显高于正常对照组(P均<0.01)。且子痫前期孕妇的VLDL-C和甘油三酯水平均与尿蛋白水平呈正相关。结论子痫前期重度蛋白尿患者体内可能存在脂代谢异常,应加强对该类患者血脂代谢情况的监测。
Objective To evaluate the relationship of blood lipid metabolism and proteinuria among preeclampsia patients. Methods Forty-one pregnant women with preeclampsia and 36 healthy pregnant women in the third trimester of pregnancy as control were enrolled. Serum levels of triglycerides, total cholesterol, low- density lipoproteins （ LDL）, high-density lipoproteins （HDL） and very low density lipoproteins （VLDL-C） were determined and compared with 24 hours urine protein of all patients. Results The VLDL-C and triglycer- ide values of pregnant women with preeclampsia were significantly higher than those of the healthy pregnant women. There was a positive correlation between increased proteinuria, higher VLDL and triglyceride levels in patients with preeclampsia. Conclusion Among patients with preeclampsia, higher VLDL and triglyceride levels were positively correlated with proteinuria.
出处
《新医学》
2013年第10期720-722,共3页
Journal of New Medicine
关键词
血脂
妊娠期高血压疾病
子痫前期
高脂血症
Lipids
Hypertension, pregnancy-induced
Pre-eclampsia
Hyperlipidemias
