摘要
目的：分析剖宫产术后深静脉血栓患者的血液系统相关指标，探讨其发病的危险因素。方法：以唐山市妇幼保健院2002年1月-2012年3月剖宫产术后2周内发生下肢深静脉血栓（DVT）的57例为病例组，排除研究资料5项以上缺失者2例，最终入选病例组55例。对照组为同年度相同时间段入住该院的未发生DVT的110例剖宫产产妇。收集活化部分凝血活酶时间（AHT）、凝血酶原时间（PT）、凝血酶时间（rrr）、纤维蛋白原（Fg）、凝血酶原国际标准化比率（PT-INR）、D-二聚体（D-Dimer）、全血高切黏度、全血中切黏度、全血低切黏度、血浆黏度、红细胞聚集指数等相关化验指标，并对其进行对比研究，对影响DVT的因素进行多因素Logistic逐步回归分析。结果：病例组D-二聚体、全血中切黏度、血浆黏度、红细胞聚集指数均高于对照组，差异均有统计学意义（P〈0．05）。结论：D-二聚体是深静脉血栓形成的独立危险因素。
Objective ： To analyze the related parameters of blood system of patients with deep venous thrombosis （DVT） after ce- sarean section, explore the risk factors of DVT. Methods ： A total of 57 patients diagnosed as DVT within two weeks after cesarean section in the hospital from January 2002 to March 2012 were selected as case group, and two patients lacking more than five items of study data were excluded, finally 55 patients were included in case group. A total of 110 parturient women after cesarean section without DVT during the same period in the hospital were selected as control group. The related laboratory indexes were collected and compared between the two groups, including activated partial thromboplastin time （AFFF）, prothrombin time （PT）, thrombin time （TF）, fibrinogen （Fg）, prothrom- bin - international normalized ratio （ FF - INR）, D - dimer, the high whole blood viscosity, the medium whole blood viscosity, the low whole blood viscosity, plasma viscosity, and RBC aggregation index. The influencing factors of DVT were analyzed by multivariate logistic stepwise regression analysis. Results ： D - dimer level, the medium whole blood viscosity, plasma viscosity, and RBC aggregation index in case group were statistically significantly higher than those in control group （ P 〈 0. 05 ） . Conclusion ： D - dimer is the independent risk factor of DVT.
出处
《中国妇幼保健》
CAS
北大核心
2013年第32期5285-5287,共3页
Maternal and Child Health Care of China
基金
河北省唐山市科技攻关项目〔121302117a〕
关键词
深静脉血栓
剖宫产术
凝血指标
Deep venous thrombosis
Cesarean section
Coagulation index
