期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

儿童EB病毒感染相关性疾病特征及分析 被引量：9

原文传递
导出
摘要 目的:探讨儿童EB病毒感染相关性疾病特征,并分析儿童EB病毒感染的不良预后因素。方法:对281例EB病毒感染患儿进行回顾性分析。结果:所分析病例中传染性单核细胞增多症占69.4%,上呼吸道感染占10.0%,支气管炎占7.5%,扁桃体炎占5.0%,肺炎占2.8%,噬血细胞综合征占1.4%,血小板减少性紫癜(ITP)占1.4%,急性肝炎占1.1%,亚急性坏死性淋巴结炎占0.7%,溶血性贫血占0.4%,再生障碍性贫血占0.4%。结论:EB病毒感染导致的疾病可以涉到呼吸系统、血液系统、消化系统、循环系统等多个系统。迁延不愈的患儿可转化为慢性EB病毒感染或噬血细胞增多综合征及恶性肿瘤,预后不良。
作者 赵欣 李春艳 宋丽君 刘晓亮
机构地区 吉林大学第一医院
出处 《中国妇幼保健》 CAS 北大核心 2013年第32期5320-5321,共2页 Maternal and Child Health Care of China
关键词 EB病毒 感染 预后
分类号 R373 [医药卫生—病原生物学]
  • 相关文献

参考文献4

二级参考文献24

  • 1仇佳晶,魏珉.幼年特发性关节炎全身型并发巨噬细胞活化综合征一例[J].中华儿科杂志,2005,43(11):874-875. 被引量：6
  • 2Kogawa K, Kee SM, Villanueva J, et al. Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members [ J ]. Blood, 2002,99 ( 1 ) : 61 - 66.
  • 3Arico M, Imashuku S, Clementi R, et al. Hemophagocytic lymphohistiocytosis due to germline mutations in SH2D1A the X - linked lymphoproliferative disease gene[ J ]. Blood,2001,97 (4) : 1131 - 1133.
  • 4Arico M, Bettinelli A, Maccario R, et al. Hemophagocytic lymphohistioctyosis in a patient with deletion of 22q11, 2 [ J ]. Am J Med Genetics, 1999,87 (4) :329 - 330.
  • 5Arico M, Imashuku S. Hemaophagocytic lymphohistiocytosis due to germline mutations in SH2DIA, the X - linked lymphoproliferative disease gene[ J]. Blood,2001,97(4) :1131 - 1133.
  • 6Jordan MB, Hildeman D, Kappler J, et al. An animal model of hemophagocytie lymphohistiocytosis(HLH) :CD8 + Tcells and interferon gamma are essential for the disorder[ J]. Blood,2004,104 ( 3 ) :735 - 743.
  • 7Schneider EM, Lorenz I, Muller - Rosenberger M, et al. Hemophagocytic lymphohistocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer - cell - induced apoptosis [ J ]. Blood,2002,100 ( 8 ) :2891 - 2898.
  • 8Groin AA, Villanueva J, Lee S, et al. NK cell dysfunction in patients with systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome [ J 3. J Pediatr,2003,142 ( 3 ) :292 - 296.
  • 9Wulffraat NM, Rijkers GT, Elst E, et al. Reduced perforin expression in systemic onset juvenile idiopathic arthritis is restored by autologous stem cell transplantation [ J ]. Rheumatology (Oxfond), 2003,42 ( 2 ) : 375 - 379.
  • 10Abbas AA, Tapp HE, Rice MS, et al. Familial hemophagocytic lymphohistocytosis : A review of six cases [ J ]. Hematology, 2004,7 ( 2 ) : 233 - 239.

共引文献70

同被引文献84

  • 1刘勇,陈琴,薛红漫,王明义.EB病毒抗体检测在儿童EBV感染相关疾病诊断中的应用价值[J].中国小儿血液与肿瘤杂志,2006,11(2):66-68. 被引量：22
  • 2王咏梅,曲熙波.EB病毒引起肝脏损害110例临床分析[J].传染病信息,2006,19(3):156-157. 被引量：7
  • 3陈正荣,季伟,王宇清,等.2006-2010年苏州地区住院儿童急性呼吸道腺病毒感染与气候因素的相关性研究[J].临床儿科杂志,2012,30(6):539-541.
  • 4Temple RM, Zhu J, Budgeon L, et al. Efficient replication of Epstein-Barr virus in stratified epithelium in vitro. Proc Natl Acad Sci USA. 2014. 111: 16544-16549.
  • 5Sen N, Mukherjee G, Sen A, et al. Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus. CellRep, 2014, 8: 633-645.
  • 6Lorenzetti MA,Altcheh J,Moroni S,et al.EBNA1 sequences in Argentinean pediatric acute and latent Epstein-Barr virus infection reflect circulation of novel South American variants[J].J Med Virol,2010,82(10):1730-1738.
  • 7Ali AS,Al-Shraim M,Al-Hakami AM,et al.Epstein-Barr virus:clinical and epidemiological revisits and genetic basis of oncogenesis[J].Open Virol J,2015(9):7-28.
  • 8Wang RC,Chang ST,Hsieh YC,et al.Spectrum of Epstein-Barr virus-associated T-cell lymphoproliferative disorder in adolescents and young adults in Taiwan[J].Int J Clin Exp Pathol,2014,7(5):2430-2437.
  • 9Daniel S,AnikóH,Judit P.Cooperation between signalling pathways leading to survival,proliferation or death of B cells[J].Ann Rheum Dis,2011,70(10):A15.
  • 10邹彩艳,文飞球,刘冯,刘智屏,李博,周克英.83例儿童急性溶血性贫血临床分析[J].中国小儿血液与肿瘤杂志,2008,13(2):71-73. 被引量：4

引证文献9

二级引证文献56

中国妇幼保健
2013年 第32期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部