摘要
目的 探讨高血压脑出血后早期的血管性认知功能障碍发生的危险因素.方法 回顾性分析本院2006-2012年收治的280例新发高血压脑出血患者的性别、年龄及血脂、血压等临床资料;所有患者均于发病30 d后采用蒙特利尔认知量表评估其是否发生血管性认知功能障碍;患者发生早期血管性认知功能障碍的危险因素分析采用Logistic回归分析.结果 多因素Logistic回归分析结果显示,高收缩压（OR=1.30,95% CI=1.09～1.55）、高糖化血红蛋白（OR=1.90,95% CI=1.73～2.08）、高超敏C反应蛋白（OR=2.90,95%CI=2.00～4.21）、关键部位出血（OR=3.10,95% CI=1.80～5.34）、高同型半胱氨酸（OR=2.72,95% CI=1.66～4.47）均进入回归方程.结论 高收缩压、高糖化血红蛋白、高超敏C反应蛋白、关键部位出血、高同型半胱氨酸是高血压脑出血患者发生早期血管性认知功能障碍的独立危险因素,治疗过程中可对这些指标进行监测.
Objective To study the risk factors of early vascular cognitive impairment in patients with hypertensive cerebral hemorrhage. Methods The general information and clinical data of the patients in our hospital with hypertensive cerebral hemorrhage were analyzed retrospectively. The vascular cognitive impairment was evaluated by MoCA. The risk factors of ear- ly vascular cognitive impairment were analyzed by Multiple Logistic Regression. Results Logistic Regression showed that high systolic pressure （OR = 1.30,95% CI = 1.09-1.55）, high glycosylated hemoglobin （OR =1.90,95% CI= 1.73-2.08）, high- sensitivity C-reactive protein（OR=2.90, 95% CI= 2.00-4.21）, hemorrhage in key parts（OR=3.10, 95% CI= 1.80-5.34） and high plasma homocysteine（OR=2.72,95% CI=1. 66-4.47） were all enter regression equation. Conclusion High systolic pressure, high glycosylated hemoglobin, high-sensitivity C reactive protein, hemorrhage in key parts and high plasma homo- cysteine were the risk factors of early vascular cognitive impairment in patients with hypertensive cerebral hemorrhage.
出处
《中国实用神经疾病杂志》
2013年第19期16-18,共3页
Chinese Journal of Practical Nervous Diseases
关键词
高血压
脑出血
血管性认知功能障碍
危险因素
Hypertension
Cerebral hemorrhage
Vascular cognitive impairment
Risk factors
