摘要
目的 根据精索静脉曲张（VC）患者的精子和生精细胞形态学特征,探讨VC的手术指征.方法 采取新鲜精液涂片,瑞-姬染色油镜观察,根据精子和生精细胞的形态特征,确定VC的手术指征.根据VC造成睾丸生精小管组织病理损伤的累积性变化和精液精子和生精细胞脱落状态,提出精子畸形率≥45%;精子头部凋亡率≥15%;生精细胞凋亡率≥20%,作为VC的手术指征和观察疗效的指标.结果 VC是慢性渐进性对睾丸生殖功能的损伤.患病时间每增加1年精液异常危险性提高0.023倍（2.3/100倍）,是非VC精液异常危险率的1.2倍.结论 VC是迁延性疾病,由于睾丸长期血运供应障碍等原因,可导致生殖功能和性功能障碍,患者应尽早、尽快手术,避免对睾丸持续性损伤,保护生殖功能和性功能.
Objective To explore the operative indication of varicocele according to the morphologm characters ot spermatozo- on and spermatogenic cells of the varicocele patients. Methods With smear of fresh semen observed with oil immersion lens microscope,identify the operative indication of varicocele according to the morphologic characters of spermatozoon and sper- matogenic cells. Based on the accumulative changes of the histopathologic damage of testicle seminiferous tubule caused by varicocele,and the castoff status of spermatozoon and spermatogenic cells, the paper points out： spermatic deformity rate≥ 45%, spermatozoon head capus apoptosis rate≥15 % ,and spermatogenic cell apoptosis rate≥20% should be used as the op-erative indication of varicocele and target to evaluate its curative effects. Results Varicocele is gradual and chronic damage to the genital function of testicle. For every additional year,the risk of abnormal semen would increase 0. 023 times,which was 20% higher than that without varicocele. Conclusion Varicocele was a prolonged disease. The long-time dysfunction of blood transportation in testicle and other reasons may cause genital and sexual dysfunction. Therefore, the patient should conduct operation as early as possible to avoid continued damage to testicle.
出处
《现代检验医学杂志》
CAS
2013年第5期1-9,共9页
Journal of Modern Laboratory Medicine
