摘要
目的:探讨柴胡桂枝干姜汤对于溃疡性结肠炎患者的临床疗效及安全性。方法:将本院收治的62例溃疡性结肠炎患者随机分为治疗组和对照组,分别给予柴胡桂枝干姜汤及柳氮磺吡啶片治疗。于治疗后对2组患者进行症状计分,并根据症状、结肠镜检查判断临床疗效,随访1年观察2组患者的复发率以及治疗期间不良反应的发生率。结果:治疗组治疗的有效率显著高于对照组的有效率(P<0.05),且治疗组腹胀、腹痛的症状评分显著低于对照组(P<0.05),治疗组复发率及不良反应发生率显著低于对照组(P<0.05)。结论:采用柴胡桂枝干姜汤治疗溃疡性结肠炎疗效确切,且不良反应发生率、复发率较低,对腹痛、腹胀症状的改善效果好,值得临床推广应用。
Objective： To investigate clinical efficacy and safety of the Chaihu Guizhi Ganjiang Decoction for patients with ulcerative colitis.Methods： Sixty-two patients with ulcerative colitis in our hospital were randomly divided into experimental and control groups,which were given Chaihu Guizhi Ganjiang Decoction or sulfasalazine pyridine tablets respectively.Clinical efficacy was evaluated by scoring the symptoms after treatment,and result of colonoscopy.Reoccurrence and the incidence of adverse reactions were followed up 1year post treatment.Results： Experimental group have shown significantly better results than the control group（P 0.05） regarding effective rate,abdominal bloating score,abdominal pain score,recurrence rate and incidence of adverse reactions.Conclusion： Chaihu Guizhi Ganjiang Decoction is effective treatment for ulcerative colitis especially for relieving abdominal pain and bloating.It has lower recurrence and lower incidence of adverse reactions compared to sulfasalazine pyridine,therefore it＇s recommendable in clinic practice.
出处
《世界中医药》
CAS
2013年第9期1051-1052,1057,共3页
World Chinese Medicine
关键词
柴胡桂枝干姜汤
柳氮磺吡啶
溃疡性结肠炎
Chaihu Guizhi Ganjiang Decoction
Sulfasalazine pyridine
Ulcerative colitis
