摘要
为探讨针刺内关抗缺血再灌注损伤作用的内在机制 ,结扎家兔左冠状动脉前降支 40min ,再灌注 1h ,观察电针内关对心肌缺血再灌注损伤血清肌酸激酶 (CK)和心肌组织丙二醛 (MDA)的影响。结果 :缺血再灌注模型组CK、MDA含量明显升高 ;针刺内关保护组与之比较显著降低 ,有非常显著性意义 (P <0 .0 1)。提示电针内关对缺血再灌注心肌的保护作用是通过减轻自由基损伤反应 ,减少心肌CK的释放 ,降低MDA的生成而实现的。
To explore the mechanism of electroacupuncture(EA) on Neiguan point on myocardial ischemia-reperfusion injury,the changes of Creatine Rinase (CK) and malondialdehyde(MDA) in blood serum were observed 40 min after myocardial ischemia and 1h after reperfasion. results:As compared with the EA group, the contents of CK and MDA of myocardial ischemia-reperfasion group were increased significantly and their differenses were also apparent(P<0.01). The present stady suggested that EA on Neiguan point had a protective role on myocardial ischemia-reperfusion by weakening injury reaction induced by free radical decreasing the releare of CK and reducing the synthesis of MDA.
出处
《湖南中医学院学报》
2000年第3期62-64,共3页
Journal of Hunan College of Traditional Chinese Medicine
基金
国家中医药管理局资助!项目 (97A10 7)
关键词
心肌缺血
再灌注损伤
肌酸激酶
MDA
电针疗法
electroacupuncture
Neiguan point
inyocardial reperfusion injury
Creatine kinase
Malodialdch.
