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小剂量糖皮质激素治疗儿童大叶性肺炎支原体肺炎的临床观察 被引量:13

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摘要 目的探讨小剂量糖皮质激素佐治儿童大叶性肺炎支原体肺炎的临床疗效。方法选取2012年6月至2013年5月本科住院治疗的大叶性肺炎支原体肺炎患儿98例,其中观察组54例,对照组44例。两组患儿均予阿奇霉素加用阿莫西林克拉维酸钾、二代或三代头孢菌素治疗1-2周,观察组在此基础上加用甲泼尼龙1-2 mg/(kg·d),2-3 d后改口服泼尼松1-2 mg/(kg·d),泼尼松量不超过20 mg/d,而后每3 d减5 mg至停药。对比两组发热和咳嗽持续时间,并且治疗10 d复查胸片了解肺炎吸收情况评价治愈率。结果观察组患儿发热持续时间及咳嗽持续时间均短于对照组,差异有统计学意义(P〈0.05);观察组治愈率(79.63%)明显高于对照组(65.91%),两组相比差异有统计学意义(P=0.000)。结论早期小剂量使用糖皮质激素佐治儿童大叶性肺炎支原体肺炎,能够较快缓解临床症状,缩短病程,提高治愈率。
出处 《中国实用医药》 2013年第28期170-171,共2页 China Practical Medicine
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参考文献12

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