期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

慢性间歇性缺氧对脂质代谢影响机制的研究 被引量：3

The preliminary study of chronic intermittent hypoxia on aorta of rats and correlated mechanism
原文传递
导出
摘要 国外流行病学调查显示，成年人阻塞性睡眠呼吸暂停低通气综合征（obstructivesleepapnea—hyponeasyndrome，OSAHS）发病率为2％～4％，老年人群发病率更高。已有研究证实，OSAHS患者三酰甘油（TG）、总胆固醇（TC）、极低密度脂蛋白（VLDL）、低密度脂蛋白（LDL）、载脂蛋白B（ApoB）、脂蛋白-a[Lp（a）]均明显升高，而高密度脂蛋白（HDL）和载脂蛋白A（ApoA）则降低，
作者 张聿炜
机构地区 湘雅二医院老年病科
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2013年第11期1238-1240,共3页 Chinese Journal of Geriatrics
基金 国家自然科学基金资助项目（30700890）
关键词 睡眠呼吸暂停 阻塞性 缺氧 脂代谢 障碍 Sleep apnea, obstructive Anoxia Lipid metabolism disorders
分类号 R766 [医药卫生—耳鼻咽喉科]
  • 相关文献

参考文献18

  • 1马晓蓉,王勇,潘磊.老年阻塞性睡眠呼吸暂停低通气综合征患者临床特点分析[J].中华老年医学杂志,2011,30(1):17-19. 被引量：1
  • 2HaderC, Schroeder A, Hinz M, et al. Sleep disordered breathing in the elderly: comparison of women and men. J Physiol Pharmaeol , 2005, 56 Suppl 4: S85-91.
  • 3朱云云,潘伟民,傅卜年,黄依琴,郭勇娟,李冬波.阻塞性睡眠呼吸暂停低通气综合征对患者心肌缺血负荷的影响[J].中国心血管杂志,2011,16(5):352-355. 被引量：5
  • 4Mary SM, Karen SL, Ho CM, et al . Serum leptin and vascular risk factors in obstructive sleep apnea. Chest, 2000,118: 580-586.
  • 5Coughlin SR, Mawdsley L, Mugarza JA, et al. Obstructive sleep apnoea is indepently associated with an increased prevalence of metabolic syndrome. Eur Heart J,2004,25:735-741.
  • 6Mary SM, MatthewMT, Kenneth WT, et al. Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit Care Med, 2002,165: 670-676.
  • 7Shamsuzzaman AS, Gersh BJ, Somers VK. Obstructive sleep apnea: implications for cardiac and vascular disease. JAMA,2003,290: 1906-1914.
  • 8Minoguchi K, Yokoe T, Tazaki T, et al. Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apnea. Am J Respir Crit Care Med,2005 ,172:625-630.
  • 9Ohga E, Tomita T, Wada H, et al. Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1. J Appl Physiol,2003,94:179-184.
  • 10Bouloumie A. Role of macrophage tissue infiltration in metabolic diseases. Curt Opin Clin Nutr Metab Care, 2005,8 : 347-354.

二级参考文献13

  • 1潘志杰,刘微波,周建英.阻塞性睡眠呼吸暂停低通气综合征老年患者的认知功能评价[J].中华结核和呼吸杂志,2005,28(6):411-412. 被引量：25
  • 2Marin JM, Carrizo SJ, Vicente E, et al. Long-term cardiovascular outcomesinmen with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure:an observational study. Lancet,2005,365 : 1046-1053.
  • 3Daltro C, Gregorio PB, Alves, et al. Prevalence and severity of sleep apnea in a group o{ morbidly obese patients. Obes Surg,2007,17 ~809 814.
  • 4Plywaczewski R, Czerniawska J, Bednarek M, et al. Influence of body weight on plasma NT-proBNP in obstructive sleep apnoea (()SA) patients. I~]ur Respir J, 2007,30 ( suppl51 ) .. 2029.
  • 5Schwartz AR, Patil SP, I.attan AM, et al. Obesity and obstructive sleep apnea~ pathogenic mechanisms and therapeutic approaches. Proc Am Thorac Soc, 2008,5..185 192.
  • 6Young T,Peppard PE, Taheri S. Excess weight and sleep-disordered breathing. J Appl Physiol, 2005 ; 99 : 1592-1599.
  • 7Haines KL, Nelson LG, Gonzalez R, et al. Objective evidence that bariatric surgery improves obesity- related obstructive sleep apnea. Surg, 2007, 141: 354 358.
  • 8Young T,Skatrud J, Peppard PE. Risk factors for obstructive sleep apnea in adults. JAMA, 2004,291: 2013-2016.
  • 9Ekici M,Ekici A, Keles H, et al. Risk factors and correlates of snoring and observed apnea. Sleep Med, 2008,9:290 296.
  • 10方丕华,张澍.心电学进展.北京:中国协和医科大学出版社,2008.104-109,132-137.

共引文献4

同被引文献28

  • 1慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华内科杂志,2007,46(3):254-261. 被引量：1790
  • 2Ljunggren M, Lindahl B, Theorell-Hagl6w J, et al. Association between obstructive sleep apnea and elevated levels of type B natriuretic peptide in a community-based sample of women[J]. Sleep, 2012, 35:1521 1527.
  • 3Goodson BL, Wung SF, Archbold KH. Obstructive sleep apnea hypopnea syndrome and metabolic syndrome= a synergistic cardiovascular risk factor [J]. J Am Acad Nurse Pract, 2012 ,24: 698-703.
  • 4Kono M, Tatsumi K, Saibara T, et al. Obstructive sleep apnea syndrome is associated with some components of metabolic syndrome[J]. Chest, 2007, 131 .. 1387-1392.
  • 5Weinberg JM. Lipotoxicity [J]. Kidney Int, 2006, 70..1560-1566.
  • 6Wende AR, Abel ED. Lipotoxicity in the heart[J]. Biochim Biophys Acta, 2010, 1801 ..311-319.
  • 7Lavie L. Oxidative stress--a unifying paradigm in obstructive sleep apnea and comorbidities [J]. Prog Cardiovasc Dis, 2009, 51..303-312.
  • 8Ling C, Elliot E, Qi Z, et al. Oxidative stress and left ventricular function with chronic intermittent hypovia in rats [J]. Am J Respir Crit Care Med, 2005, 172..915-920.
  • 9Williams AL, Chen L, Scharf SM. Effects of allopurinol on cardiac function and oxidant stress in chronic intermittent hypoxia [J ]. Sleep Breath, 2010,14..51-57.
  • 10Winterbourn CC, Kettle AJ. Reactions of superoxide with myeloperoxidase and its products [J]. Jpn J Infect Dis, 2004, 57..31-35.

引证文献3

中华老年医学杂志
2013年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部