摘要
以十二烷基磺酸钠 (SL S)为胶束试剂 ,在优化的实验条件下 ,对兔体血浆中丹参酮 A的血药浓度进行了 2 4 h的连续监测 ,检出限为 1 .2× 1 0 -9g/ m L ,血中丹参酮 A的含量在 2 .81× 1 0 -6～ 0 .30× 1 0 -6g/ m L之间。该法简便、灵敏。
Using SLS as a micella reagent, the blood drug concentration of tanshione Ⅱ A in rabbit blood was monitored continously for 24 h under the optimized conditions. The detection limit was 1.2×10 -9 g/mL. The results showed that there was 2.81×10 -6 ~0.30×10 -6 g/mL of tanshinone Ⅱ A in blood. The proposed method was simple and sensitive with good results.
出处
《分析科学学报》
CAS
CSCD
2000年第6期488-491,共4页
Journal of Analytical Science
关键词
胶束荧光
丹参酮Ⅱ_(A)
血药浓度
Micella fluorometry
TanshinoneⅡ_(A)
Blood-drug concentration
