摘要
运用核苷酸补救途径理论 ,采用枯草杆菌肌苷产生菌 ,在培养过程中添加次黄嘌呤 ,作为从头合成途径 (denovo)的补充 .此方法应用于工业化生产 ,肌苷产率大幅提高 .
Applying the theory of “nucleotide salvage”,we added the hypoxanthine to culture process of inosine producing mutants of Bacillus subtilis as supplement of de novo formation of inosine which made inosine synthesis improved greatly.It illustrates that method is valuable in industrial application.
出处
《山东大学学报(自然科学版)》
CSCD
2000年第4期453-457,共5页
Journal of Shandong University(Natural Science Edition)