摘要
目的 探讨乌鲁木齐地区结节性甲状腺肿、桥本氏甲状腺炎与尿碘含量间关系.方法 采用病例对照研究方法,将该地区结节性甲状腺肿患者132例,桥本氏甲状腺炎患者47例作为病例组,另选同地区甲状腺正常的300例健康者作为对照组,采用过硫酸铵消化砷铈催化分光光度法采集受试者空腹晨尿,测定尿碘含量.结果 结节性甲状腺肿患者尿碘均数为（294.06±132.24） μg/L,其中碘过量者（尿碘＞300 μg/L）63例,占47.7％ （63/132）；桥本氏甲状腺炎尿碘均数为（306.74±211.85） μg/L,碘过量21例,占44.7％ （21/47）；对照组尿碘均数为（161.40±125.25） μg/L,碘过量30例,占10％（30/300）,两病例组尿碘均数及碘过量者均显著高于对照组（P＜0.05）.结论 本地区部分结节性甲状腺肿与桥本氏甲状腺炎患者碘营养状况高于一般人群,与其发病可能有一定关系,提倡在低碘地区也不能过度补碘,应通过尿碘检测科学补碘,防止因碘过量导致甲状腺疾病.
Objective To investigale the relationship between thyroid nodal disease, Hashimoto＇ s thyrolditis and urine iodine in Urumqi. Methods A case-control study was done on 132 cases of thyroid nodal disease, and 47 cases of Hashimoto＇ s thyrolditis treated in Tumor Hospital as the case group, and 300 volunteers with normal thyroid function from the examination Center of the same hospital served as the control group. The urine iodine concentration was determined by using arsenic-cerium catalytic spectropho- tometry. Results The mean urinary iodine in the case group with thyroid nodal disease was （294. 06 ± 132. 4）μg/L, and there were 63 cases of excessive iodine intake （urinary iodine 〉 300 μg/L） , account- ing for 47.7% （63/132）. The mean urinary iodine level in Hashimoto＇ s thyrolditis group was （306. 74±＋ 211.85） μg/L, and there were 21 cases of excessive iodine intake （urinary iodine 〉 300 μg/L） , ac- counting for 44. 7% （21/47）. The mean urinary iodine in control group was （ 161.40 ±125.25） μg/L, and there were 30 cases of excessive iodine intake （urinary iodine 〉 300 μg/L） , accounting for 10% （30/300）. The excessive iodine intake levels in the two case groups were higher than in the control group （ P 〈 0. 05 ）. Conclusion The iodine nutritional status in patients with thyroid nodal disease and Hashimo- to＇ s thyrolditis is better than the general population, and there is a relationship between the thyroid-related diseases and excessive iodine intake.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2013年第11期2394-2396,共3页
Chinese Journal of Experimental Surgery
基金
新疆维吾尔自治区自然科学基金资助项目（2012211）
关键词
结节性甲状腺肿
尿碘
Thyroid carcinoma
Urine iodine
