摘要
目的 使用盐酸哌罗匹隆治疗精神分裂症,分析其疗效并对副作用进行评价.方法 选择2012年12月～2013年5月的56例患者作为研究对象,所有患者的确诊均按照中国精神分裂诊断标准进行.将其随机分为两组,每组28例.使用阳性、阴性症状量表等作为判定疗效的标准,同时对两组的疗效及副作用等进行统计学分析.结果 对照组的有效率为92.9％,实验组有效率为96.5％,差异无统计学意义（P＞0.05）;两组患者在同一时间点的阴性、阳性症状量表评分及其他因子评分无明显差异（P＞0.05）;两组患者不良反应无显著差异（P＞0.05）.结论 盐酸哌罗匹隆与阿立哌唑的效果相似,此药为一种新型的、非典型性的抗精神病药物,且对机体伤害较小、不良反应少、疗效较好,可以在治疗精神分裂症的领域进行推广使用.
Objective To evaluate the efficacy and side effects of perospirone hydrochloride hydrate in the treatment of schizophrenia. Methods A total of 56 cases of patients who were diagnosed as schizophrenia by diagnostic criteria for schizophrenia and admitted to our hospital from December 2012 to May 2013 were randomly divided into two groups, 28 cases in each group. By using positive and negative symptoms scale as the standard, the curative effect and side ef- fects of the two groups were statistically analyzed. Results The effective rate of control group was 92.9%, while the ex- perimental group was 96.5%, the difference between the two groups was not statistically significant （P 〉 0.05）; there were no significant difference between the two groups in the scores of positive and negative symptoms, and other factors at each time point （P 〉 0.05）; the adverse reactions between the two groups was not statistically significant （P 〉 0.05）. Conclusion The effect of perospirone hydrochloride hydrate is similar with aripiprazole, it＇s a kind of new and atypi- cal antipsyehotic drugs, has less injury to the body, less adverse reactions, and the curative effect is good, so it can be widely used in the field of schizophrenia.
出处
《中国现代医生》
2013年第32期75-77,共3页
China Modern Doctor
基金
江苏省卫生厅面上科研课题项目(H201043)
关键词
精神分裂症
药物治疗
盐酸哌罗匹隆
阿立哌唑
Schizophrenia
Drug therapy
Perospirone hydrochloride hydrate
Aripiprazole
