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CPP-ACP与不同浓度氟促进釉质再矿化的研究 被引量:3

Remineralization of enamel promoted by casein phosphopeptide-amorphous calcium phosphate with different concentration of fluorin
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摘要 目的:探讨酪蛋白磷酸多肽-无定形磷酸钙(casein phosphopeptide-amorphous calcium phosphate,CPP-ACP)与不同浓度氟离子联合应用对脱矿釉质再矿化的作用。方法:取正畸拔除的健康前磨牙30颗,乳酸凝胶法制备人工早期釉质脱矿后,随机分为对照组(5%CPP-ACP组)、实验组1(5%CPP-ACP+500 mg/L F-组)和实验组2(5%CPPACP+900 mg/L F-组),采用MH-5型显微硬度仪测量处理前、后釉质标本的显微硬度,采用SPSS 18.0软件包对数据进行统计学分析。结果:显微硬度测量显示,实验组2牙釉质的表面显微硬度变化显著高于实验组1(P<0.05)及对照组(P<0.01)。结论:CPP-ACP能够促进脱矿釉质再矿化,氟对其有加强协同作用。在一定范围内,氟浓度越高,协同作用越好。 PURPOSE: To evaluate the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) combined with different concentrations of fluoride on demineralization of enamel remineralization. METHODS: Extracted premolar teeth for orthodontic reason were immersed into lactic acid gel to prepare artificial white spot lesions. Then the specimens were randomly assigned to 3 groups: 5% CPP-ACP group as control, 5% CPP-ACP +500 mg/L F^- group and 5% CPP-ACP +900 mg/L F^- group, which were measured by micro-hardness tester. SPSS 18.0 software package was used for data analysis. RESULTS: There were significant differences in micro-hardness between control group and experimental group 1 and experimental group 2 by SNK-q test (P〈0.05). CONCLUSIONS: CPP-ACP can make the demineralization of enamel remineralization occurs. F can promote the CPP-ACP remineralization. The increase of fluoride can make the CPP-ACP remineralization better below 1000-1500 mg/L.
出处 《上海口腔医学》 CAS CSCD 北大核心 2013年第5期533-536,共4页 Shanghai Journal of Stomatology
关键词 酪蛋白磷酸多肽-无定形磷酸钙 再矿化 显微硬度 APP-ACP Florid Enamel remineralization Micro-hardness
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参考文献13

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二级参考文献18

  • 1赵琼芝,蔡璠.酪蛋白磷酸多肽钙氟磷复合体对牙釉质缺损再矿化的实验研究[J].中华口腔医学杂志,2001,36(6):24-26. 被引量:13
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