摘要
目的探讨子宫内膜异位症(内异症)相关不孕患者年龄、r-AFS分期(根据1985年修订的美国生育学会内异症分期标准)、不孕类型、不孕年限、术前用药、术后用药及是否接受辅助生殖技术助孕与腹腔镜术后妊娠率的关系。方法对101例内异症相关不孕患者腹腔镜术后妊娠情况进行回顾性分析。结果①术后1年内妊娠率显著高于术后1年后妊娠率。②术后1年内仅年龄、是否采用辅助生殖技术助孕影响术后妊娠率。③术后1年后仅年龄影响术后妊娠率。④多因素logistic回归分析显示年龄是术后妊娠率的独立影响因素。结论年龄是腹腔镜术后妊娠率恒定独立影响因素。对术后短期期待、经指导受孕而未能妊娠的患者,特别是年龄≥35岁的患者,建议积极采用辅助生殖技术助孕。
Objective To explore the relationship between pregnancy rate and the factors including age, the staging according to the revised American Fertility Society classification （r-AFS, 1985）, the infertility type and duration, suppressive medical therapy before or after surgery and assisted reproductive technology（ART） offer in patients with endometriosis（EM） associated infertility after laparoscopic surgery. Methods A total of 101 patients with EM associated infertility underwent laparoscopic treatment were studied retrospectively. Results ① The pregnancy rate of the first year was significantly higher than that of the second to fourth years.② Age and ART offer had significant effects on the pregnancy rate while the other factors had no effects within one year. ③Age was the only factor which had significant effect on the pregnancy rate after one year. ④Age was the only independent factor which was associated with the pregnancy rate as shown by the logistic regression analysis. Conclusion Age is the only factor which affected pregnancy rate constantly and independently. ART should be adored early to achieve pregnancy if short-term expectant management and guide for natural conception could not work.
出处
《中国实用医药》
2013年第31期1-3,共3页
China Practical Medicine
基金
福建省科技计划重点项目(项目编号:2011Y0010)
