摘要
药物性肝损伤是由于药物和(或)其代谢产物引起的肝细胞毒性损伤,或药物及其代谢产物引起的过敏反应所致的疾病。因其发生范围广,预测性差,且无特异性治疗方案,日益成为威胁人类健康的"隐形杀手"。本文针对药物性肝损伤的研究现状和存在问题进行探讨,以期加强临床医生在用药时的关注。
Drug-induced liver injury （DILI） is a type of hepatotoxicity damage caused by drugs and/or their metabolites, or the disease caused by allergic reactions to drugs and their metabolite. DILI is an invisible killer and threatens human health due to a wide occurrence, poor predictability and no specific treatment strategies. In this paper, the research status and existing problems of DILI are discussed for improving clinicians＇ attention to the use of drugs.
出处
《传染病信息》
2013年第5期263-265,275,共4页
Infectious Disease Information
关键词
药物性肝损伤
肝疾病
肝功能衰竭
drug-induced liver injury
liver diseases
liver failure
