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脾动脉栓塞治疗肝硬化继发脾脏功能亢进的临床效果观察 被引量:5

Clinical effect of splenic artery embolization on treatment of hepatic cirrhosis complicated with hypersplenism
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摘要 目的 探讨脾动脉栓塞术(PSE)治疗肝硬化继发脾脏功能亢进的临床效果.方法 选取我院肝硬化继发脾脏功能亢进患者80例,其中研究组48例,行脾动脉栓塞术;对照组32例,行脾脏切除术,比较两组患者的出血量、住院时间、术后恢复、并发症等.结果 与对照组比较,研究组患者的住院时间缩短、出血量减少,差异有统计学意义(P<0.05);两组患者术后不良反应比较,差异无统计学意义(P >0.05);PSE后脾局部梗死后门静脉内径减小,与对照组比较差异无统计学意义(P>0.05).结论 PSE治疗肝硬化继发脾脏功能亢进临床效果显著,微创易恢复,门静脉宽度变窄,门脉压力降低. Objective To explore the clinical effect of splenic artery embolization(PSE) in treating hepatic cirrhosis complicated with hypersplenism.Methods Eighty cases of hepatic cirrhosis complicated with hypersplenism were recuited,48 cases in treatment group received PSE,and 32 cases in control group received slenectomy.Clinical data were compared including the amount of bleeding,hospital stay,postoperative recovery,complications and other symptoms.Results Hospital time and the amount of bleeding decreased in treatment group than those in control group (P < 0.05) ; whereas postoperative adverse reaction has not change between the two groups (P > 0.05) ;With PSE after splenic infarction,inner diameter of portal vein reduced,the difference was not statistically significant between these 2 groups (P > 0.05).Conclusion PSE in the treatment of hepatic cirrhosis complicated with hypersplenism has significant clinical effects.It is minimally invasive.With this treatment,micro wound is easy to recover,the width of portal vein becomes narrower,and the portal pressure decreases.It is a convenient and safe treatment,and is worthy of applicating in clinic.
出处 《临床内科杂志》 CAS 2013年第10期686-687,共2页 Journal of Clinical Internal Medicine
关键词 脾动脉栓塞 肝硬化继发脾脏功能亢进 Splenic artery embolization Hepatic cirrhosis complicated with hypersplenism
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