摘要
目的探讨鼻塞式气道正压通气联合肺表面活性物质治疗新生儿呼吸窘迫综合征的临床疗效。方法给42例患有呼吸窘迫综合征的新生儿行气管插管,经气管内滴入肺表面活性物质,给予持续性气道正压通气呼吸支持治疗。结果患儿治疗前与治疗后相比较,血气分析各项指标(PaO2、氧和指数PaO2/FiO2、pH值、PaCO2变化情况)及机械通气各项指标(吸入氧浓度FiO2、通气频率RR、峰压PIP、呼气末正压PEEP的变化情况)有显著好转(P<0.01)。结论对早产儿呼吸窘迫综合症而言,持续性气道正压通气联合肺表面活性物质能迅速有效地改善患儿临床症状,提高了患儿的抢救成活率。
Objective To observe the clinical effect of nasal continuous positive airway pressure and pulmonary suffactant in the treatment of neonates with respiratory distress syndrome. Methods 42 neonates with respiratory distress syndrome were treated with pul- monary surfaetant and then were given breath support by nasal continuous positive airway pressure. Results Compared with before and af- ter the treatment, the blood gas analysis indexes （ PaO2 ,PaO2/FiO2 ,pH ,PaCO2 ） and mechanical ventilation （ FiO2 ,RR,PIP ,PEEP） were significantly improved（P 〈 0. 01 ）. Conclusion Continuous positive airway pressure application combined with pulmonary surfactant is effective and safe in the treatment of neonates with respiratory distress syndrome, which can improve their survival rate.
出处
《临床肺科杂志》
2013年第12期2197-2198,共2页
Journal of Clinical Pulmonary Medicine
关键词
持续性气道正压通
肺表面活性物质
呼吸窘迫综合征
nasal continuous positive airway pressure
pulmonary surfactant
respiratory distress syndrome
