期刊文献+

64排螺旋CT冠状动脉血管成像和冠状动脉血管造影对老年冠心病合并2型糖尿病患者冠状动脉病变诊断的对比研究 被引量:16

Clinical Comparison Analysis of 64-MSCTA and Coronary Angiography for Detecting Coronary Stenosis in Elderly Patients with Coronary Artery Disease Combined with Type 2 Diabetes Mellitus
下载PDF
导出
摘要 目的通过与冠状动脉血管造影比较,评价64排螺旋CT冠状动脉血管成像在老年冠心病合并2型糖尿病患者冠状动脉病变诊断中的价值。方法 2010年1月至2011年12月在昆明医科大学第一附属医院经64-MSCTA疑诊为冠心病且合并糖尿病的患者68例,1个月内行冠状动脉血管造影检查,将两种检查结果进行对比分析。结果 64排螺旋CT对诊断冠状动脉狭窄的灵敏度为90.67%,特异度为91.67%,阳性预测值80.73%,阴性预测值96.23%,准确率为91.39%,两种检查方法在诊断冠状动脉有无狭窄病变上差异无统计学意义(P<0.05)。68例合并糖尿病的老年冠心病患者冠脉斑块以软斑块最多见,占48.04%(98/204),引起管腔轻度狭窄的多为钙化性斑块(52%,26/50),引起管腔中重度狭窄的多为软斑块及混合性斑块(84.42%,130/154)。结论 64排螺旋CT冠状动脉成像技术是一种安全、简便、可靠的无创性检查技术,是评价冠状动脉病变的重要手段。 Objective To evaluate the diagnosis value of 64-muhislice spiral computed tomography angiography(64-MSCTA) for the assessment of coronary artery disease with type 2 diabetes mellitus in comparison with invasive coronary angiography. Methods Both 64-MSCTA and conventional coronary angi- ography(CAG) were performed in 68 elderly patients who were suspected of having coronary artery disease combined with Type 2 diabetes mellitus recruited from the patients in the First Affiliated Hospital of Kunming Medical University during January 2010 and December 2012. All the patients had coronary angiography in one month and the results were compared and analyzed. Results The sensitivity of 64-MSCTA for detecting coronary artery stenosis was 90.67% ,the specificity was 91.67%, veracity was 91.39%. The positive and negative predictive values were 80.73% and 96.23%, respectively. Further analysis showed no statistically significant difference in the discovery of coronary artery disease between 64-MSCTA and CAG( P 〈 0.05 ), According to the analysis of the 64-MSCTA,it was found that among 68 elderly patients with coronary artery disease and type 2 diabetes meIIitus, and the majority of coronary plaques were soft and unstable in nature (48.04% ,98/204 ). Medium to severe lumen stenosis was caused by soft and complex plaques (84.42%, 130/ 154 )while s!ight lumen stenosis was caused by calcified plaques( 52% ,26/50 ). Conclusion 64-MSCTA is a safe, reliable and noninvasive diagnostic technology which can be used as the preferred method of screening for coronary artery disease with type 2 diabetes mellitus.
出处 《医学综述》 2013年第20期3787-3789,共3页 Medical Recapitulate
关键词 冠心病 2型糖尿病 64排螺旋CT冠状动脉成像 冠状动脉造影 Coronary artery disease with type 2 diabetes meilitus 64-multislice spiral computed tomo- graphy angiography Coronary angiography
  • 相关文献

参考文献8

  • 1Austen WG, Edwards JE, Frye RL, et al. A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc committee for grading of coronary m-ery disease, council on cardio- vascular surgery, American heart association [ J ]. Circulation, 1975, 51 (4 Suppl) :5-40.
  • 2Lesehka S, Alkadhi H, Plass A, et al. Accuracy of MSCT coronary angiography with 64-slice technology:first experience [ J ]. Eur Heart J,2005,26( 15 ) : 1482-1487.
  • 3Mollet NR, Cademartiri F, van Mieghem CA, et al. High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography[ J ]. Cireu- lation ,2005,112 ( 15 ) : 2318-2323.
  • 4金晓东,刘锡强,陈文强,李继福,孙金玲,刘海宁,李玉花,黄光明.64排螺旋CT在老年冠心病合并糖尿病患者冠脉病变诊断中的应用[J].山东医药,2011,51(35):83-85. 被引量:12
  • 5Nikolaou K, Knez A, Rist C, et al. Accuracy of 64-MDCT in the diagnosis of ischemic heart disease [ J ]. A JR Am J Roentqenol, 2006,187(1) :111-117.
  • 6Pundziute G,Schuijf JD, Jukema JW, et al. Noninvasive assessment of plaque characteristics with multislice computed tomography coro- nary angiography in symptomatic diabetic patients [ J ]. Diabetes Care,2007,30(5) :1113-1119.
  • 7李锦,赵均雄,冯晓荣,梁立华,吴菊芳.64层螺旋CT与血管内超声对冠状动脉斑块特征评价的精确性比较[J].南昌大学学报(医学版),2012,52(4):35-36. 被引量:9
  • 8Briguori C, Airoldi F, Morici N,et al. New pharmacological protocols to prevent or reduce contrast media nephropathy [ J ]. Minerva Cardioangio1,2005,53 ( 1 ) :49-58.

二级参考文献16

  • 1韩志华,何奔,王长谦,王彬尧,厉锦华,张清,刘建平,郑道声.不稳定型心绞痛患者的血管内超声分析[J].临床心血管病杂志,2005,21(12):711-713. 被引量:13
  • 2柯元南,陈纪林.不稳定性心绞痛和非ST段抬高心肌梗死诊断与治疗指南[J].中华心血管病杂志,2007,35(4):295-304. 被引量:2146
  • 3Windecker S,Maier-Rudolph W,Bonzel T,et al.Interventional cardiology in Europe 1995[J].Eur Heart J,1999,20(7):484-495.
  • 4Juutilaine A,Lehto S,Rǒnnemaa T.Type 2 Diabetes as A "Coronary Heart Disease Equivalent" an 18-Year Prospective Populationbased Study in Finish Subjects[J].Diabetes Care,2007,28(12):2901-2907.
  • 5Mullet NR,Cademartiri F,Neman K,et al.Multi-slice spiral CT coronary angiography in patients with stable angina pectoris[J].J Am Coll Cardiol,2004,43(12):2265-2270.
  • 6Schroeder S,Kopp AF,Bauboch A,et al.Noninvasive detection of coronary lesions by multi-slice computed tomography:result of the new age pilot trail[J].Catheter Cardiovascular Interval,2001,53(3):352-358.
  • 7Mullet NR,Cadem F,van Mieghem CA,et al.High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography[J].Circulation,2005,112(10):2318-2323.
  • 8Niemen K,Cademartiri F,Lemons PA,et al.Reliable noninvasive coronary angiography with fast sub millimeter multi-slice spiral computed tomography[J].Circulation,2002,106(10):2051-2054.
  • 9Alexander W,Leber AW,Andreas Knez,et al.Quantification of obstructive and nonobstructive coronary lesion by 64-Slice computed tomography,a comparative study with quantitative coronary angiography and intravascular ultrasound[J].Am Coll Cardiol,2005,46(1):47-54.
  • 10Raff GL,Michael J,Gallagher MJ,et al.Diagnostic accuracy of noninvasive coronary angiography using 64-Slice computed tomography[J].Am Coll Cardiol,2005,46(55):2-7.

共引文献19

同被引文献120

引证文献16

二级引证文献73

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部