摘要
目的 观察兰索拉唑治疗消化系统溃疡的临床效果及不良反应.方法 选取本院2011年11月~2012年12月收治的86例消化系统溃疡患者,将其分成治疗组(43例)和对照组(43例).治疗组患者采用兰索拉唑治疗,对照组患者采用奥美拉唑治疗,对比两组患者的治疗效果及不良反应发生率.结果 治疗组患者的总有效率为93.02%,幽门螺杆菌根除率为90.70%;对照组患者的总有效率为76.74%,幽门螺杆菌根除率为67.44%,两组间比较,差异均有统计学意义(P<0.05).两组患者不良反应发生率均为2.33%,差异无统计学意义(P>0.05).结论 兰索拉唑治疗消化系统溃疡效果良好,不良反应较低,值得推广应用.
Objective To observe the clinical effects and adverse reactions of lansoprazole for the treatment of peptic ulcer. Methods 86 patients with peptic ulcer in our hospital from November 2011 to December 2012 were selected as research objects and patients were divided into treatment group(n=43) and control group(n=43),the treatment group re- ceived lansoprazolc and the control group received omeprazole,then treatment effect and adverse reaction incidence be- tween the two groups were compared. Results The total effective rate and Hp eradication rate of the treatment group was 93.02% and 90.70% respectively,the total effective rate and Hp eradication rate of the control group was 76.74% and 67.44% respectively.The difference were all statistically significant (P〈0.05);the adverse reaction incidence was 2.33% in both groups,the difference was not statistically significant (/%0.05). Conclusion Lansoprazole can be widely applied for treating peptic in both groups ulcer due to its better clinical efficacy and lower adverse reaction incidence.
出处
《中国当代医药》
2013年第31期78-79,共2页
China Modern Medicine