期刊文献+

宫颈癌患者淋巴结转移的影响因素分析 被引量:17

Analysis of Factors Affecting Lymph Node Metastasis of Cervical Cancer
下载PDF
导出
摘要 目的探讨宫颈癌患者淋巴结转移的分布规律、高危因素。方法选取均经活检或手术病理证实的71例宫颈癌患者为研究对象,对影响淋巴结转移的因素采用Logistic多因素回归分析。结果 71例宫颈癌患者中有14例患者发生淋巴结转移,转移率为19.7%;单因素分析结果显示肿瘤直径、SCCAg水平、FIGO分期、病理分型、肌层浸润深度、脉管侵犯、分化程度与淋巴结转移相关(P<0.05),而年龄、手术切缘与淋巴结转移不具相关性(P>0.05);Logistic多因素回归分析结果显示治疗前SCCAg水平、脉管侵犯、FIGO分期、肌层浸润深度以及分化程度5个因素是淋巴结转移的独立危险因素。结论治疗前SCCAg>4 ng/ml、宫颈浸润深度≥肌层1/2、脉管侵犯、FIGO分期较晚及细胞分化程度较高是宫颈癌盆腔淋巴结转移的主要危险因素。 Objective To study the distributional features and high-risk factors of lymph node metastasis of cervical cancer. Methods 71 cases of cervical cancer patients confirmed by biopsy or surgical pathology were selected as the research object,and the logistic muhifactor regression analysis was used to analyze the influencing factors of lymph node metastasis. Results Among 71 cervical cancer patients, 14 cases had lymph node metastases, the metastasis rate was 19.7% ; Single factor analysis showed that tumor diameter, SCCAg level, FIGO stage, pathological type, muscularis infiltrating depth, vascular invasion, differenti- ation degree were related to lymph node metastasis( P 〈 O. 05 ), while there was no correlation among age, surgical cut edge and lymph node metastasis(P 〉 0.05 ); Logistic multifactor regression analysis showed that SCCAg level, vascular invasion, FIGO staging, muscularis infiltrating depth and differentiation degree were 5 independent risk factors of lymph node metastasis before the treatment. Conclusion Before treatment, SCCAg 〉 4 ng/ml, the cervical infiltration depth equal or greater than 1/2 of muscular layer, vascular invasion,late FIGO staging and high degree of cell differentiation are the major risk factor of cervical cancer pelvic lymph node metastasis.
作者 蒋乐萍
出处 《实用癌症杂志》 2013年第6期731-733,共3页 The Practical Journal of Cancer
关键词 宫颈癌 淋巴结转移 危险因素 Cervical cancer Lymph node metastasis Risk factors
  • 相关文献

参考文献12

二级参考文献74

共引文献78

同被引文献120

  • 1顾颖,韩素萍,张晔.RhoA、RAC1在宫颈癌组织中的表达及其临床意义[J].苏州大学学报(医学版),2008,28(1):115-118. 被引量:4
  • 2冯淑瑜,张彦娜,刘建刚.宫颈癌淋巴结转移的高危因素及预后分析[J].癌症,2005,24(10):1261-1266. 被引量:71
  • 3于月成,辛晓燕,吴维光,李红梅,李奇灵.Rho和ROCK蛋白在上皮性卵巢癌中的表达及临床意义[J].现代肿瘤医学,2006,14(4):461-464. 被引量:24
  • 4辛海量,胡园,张巧艳,郑汉臣,秦路平.正交试验优选蔓荆子提取工艺研究[J].药学服务与研究,2006,6(5):342-344. 被引量:3
  • 5Stephanie C.Han,章青,陆嘉德.大肿块ⅠB、ⅡA期及局部晚期宫颈癌的治疗[J].中国癌症杂志,2006,16(11):890-895. 被引量:7
  • 6Sergio Pecorelli.Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium[J]. International Journal of Gynecology and Obstetrics . 2009 (2)
  • 7Bradley J. Monk,Jianmin Wang,Samuel Im,Richard J. Stock,William A. Peters,P.Y. Liu,Rolland J. Barrett,Jonathan S. Berek,Luis Souhami,Perry W. Grigsby,William Gordon,David S. Alberts.Rethinking the use of radiation and chemotherapy after radical hysterectomy: a clinical–pathologic analysis of a Gynecologic Oncology Group/Southwest Oncology Group/Radiation Therapy Oncology Group trial[J].Gynecologic Oncology.2004(3)
  • 8Martinez A, Mery E, Filleron T, et al. Accuracy of intraoperative pathological examination of SLN in cervical cancer. Gynecol Oncol, 2013,130(3) : 525-529.
  • 9Lee J, Song Y, Soh E Y. Prognostic significance of the number of metastatic lymph nodes to stratify the risk of recurrence. World J Surg,2014,38(4) : 858-862.
  • 10Reade C J, Eiriksson L R, Covens A. Surgery for early stage cervical cancer:how radical should it be? Gynecol 0ncol,2013,131 (1): 222-230.

引证文献17

二级引证文献136

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部