摘要
目的探讨节拍化疗联合艾迪注射液治疗恶性肿瘤的临床疗效。方法将78例恶性肿瘤患者随机分为2组,A组38例实施常规化疗,B组40例实施节拍化疗联合艾迪注射液治疗,观察2组治疗效果及生活质量改善情况。结果 B组总缓解率为70.00%,高于A组的50.00%(P<0.05);B组卡氏评分(KPS)改善率为82.50%,高于A组的50.00%(P<0.05);B组节拍化疗联合艾迪注射液治疗恶性肿瘤,可显著提高肿瘤细胞控制率,改善患者生活质量,减少不良反应,值得临床推广应用。B组Ⅱ～Ⅴ级不良反应发生率显著低于A组(P<0.05)。结论节拍化疗联合艾迪注射液治疗恶性肿瘤,可显著提高肿瘤细胞控制率,改善患者生活质量,减少不良反应,值得临床推广应用。
Objective To observe the clinical efficacy of metronomic chemotherapy combined with Aidi injection for malignancy. Methods 78 patients with malignant tumors were randomly divided into the 2 groups ,38 cases in group A were given conventional chemotherapy, while 40 cases in group B were given metronomic chemotherapy combined with Aidi injection, curative effect and improvement of quality of life of the 2 groups were observed. Results Overall response rate of group B was 70.00% , which was higher than of group A （50.00% , P 〈 0.05 ） ;Karnofsky score （KPS） improvement rate of group B was 82.50% , which was higher than that of group A （ 50.00% , P 〈 0.05 ） ; Grade Ⅱ～Ⅴ toxicity incidence rate of group B was lower than that of group A. Conclusion Metronomic chemotherapy combined with Aidi injection for malignant tumors can significantly improve the tumor cell control rate, improve the quality of life of patients and reduce the toxicity,it is worthy of clinical application.
出处
《实用癌症杂志》
2013年第6期759-761,共3页
The Practical Journal of Cancer
