摘要
环境激素(environmental endocrines,EEs)是外源性激素,可模拟体内天然激素与机体内的受体以及相应靶点结合,导致内分泌系统以及生殖系统功能紊乱。环境激素所产生的效应十分复杂,因此,进一步明确其毒性机理将为环境激素所致危害的预防和治疗提供理论依据。就环境雌激素的生殖、发育等毒性机理作一综述。
Environmental endocrines （EEs） are environmental hormones which bind receptors and the targets by imitating natural hormones and result in endocrine system and reproductive system disorders. The effects of EEs are very complex. Thus, further studies on its molecular mechanisms will provide theoretic basis for the treatment and prevention of toxicity of EEs. This paper reviewed the toxicity mechanisms of environmental estrogens on reproduction and development.
出处
《生命科学》
CSCD
2013年第11期1121-1125,共5页
Chinese Bulletin of Life Sciences
基金
昆明理工大学医学神经生物学重点实验室项目(14078142)和创新团队
关键词
环境激素
环境
雌激素
生殖
environmental hormone
environment
estrogens
reproduction
