摘要
目的了解中医药治疗糖尿病前期随机对照文献质量情况。方法以"糖尿病前期;葡萄糖调节受损;葡萄糖耐量受损;空腹血糖受损"为检索词,收集中医药治疗糖尿病前期随机对照的文献,应用简易法进行文献质量评价。结果共纳入60篇随机对照试验文献,5008例患者,有18.33%的文献标明有基金支持,各年份发表的文献基本呈逐年递增的趋势,尤其近5年的研究论文逐渐增多,在随机化原则上,大部分研究采取不正确的随机方法,并且分配方案的隐藏常常被研究者忽视或者未报告。盲法的运用较少(3.33%),大部分文献没有报告研究样本量估算方法和研究流程图,大部分文献的质量等级为C级。结论目前国内中医药防治糖尿病前期的高质量临床研究报道较少,现有研究总体质量有待提高。
Objective： To Learn the quality of randomized controlled literature about Chinese medicine treatment prediabetes. Methods： literature about Chinese medicine treatment prediabetes were searched by the Title or keywords such as pre-diabetes,impaired glucose regulation,impaired glucose tolerance,impaired fasting glucose. Literatures about randam control trails of traditional Chinese Medicine therapy for prediabetes were searched.And the quality of these literatures were assessed by simple method. Results： 60 randomized controlled trials articles （5008 patients） were found, 18.33% of which had fund to support. Articles published each year showed an in- creasing trend, especially in the last five years.Lots of articles used wrong stochastic methods. Allocation conceal- ment were often overlooked by researchers,or not reported. Blinding was rarely applied （3.33%）, and lots of arti- cles had not reported sample estimation method and research flowchart. Quality grade of lots of articles were C- level. Conclusion： The number of literatures with high quality about Chinese medicine treatment prediabetes is still less, and the quality of them needs to be improved.
出处
《中国中医急症》
2013年第11期1827-1829,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
国家中医临床研究基地业务建设科研专项课题(JDZX2012002)
安徽中医学院临床科学研究基金项目(2010LC-007A)
