期刊文献+

T-SPOT.TB在菌阴肺结核中的诊断价值 被引量:10

The Value of T-SPOT.TB in Diagnosis of Smear-negative Pulmonary Tuberculosis
下载PDF
导出
摘要 目的:评价γ干扰素释放结核感染T细胞斑点试验(T-SPOT.TB)检测在菌阴肺结核中的诊断价值。方法:将本院住院确诊菌阴肺结核67例患者作为观察组,同期入住的124例肺炎患者作为对照组,两组进行T-SPOT.TB、结核抗体、结核菌素试验(PPD)等检测。结果:T.SPOT.TB在菌阴肺结核组中的敏感性(89.6%)和特异性(91.1%)均高于对照组,比较差异均有统计学意义(P<0.01)。结论:T-SPOT.TB在诊断菌阴肺结核方面具有较高的敏感性和特异性,对菌阴肺结核有着重要的诊断价值。 Objective: To evaluate the diagnostic value of T-SPOT.TB in smear negative pulmonarytuberculosis.Method: Sixty-seven smear negative tuberculosis patients ( the observation group ) and 124 pneumonia patients ( the control group ) were enrolled in the test.The two groups were given γ-SPOT.TB, PPD and tuberculosis antibody ( TBAb ) test.Result: The sensibility and specificity of T-SPOT.TB test in observation group were 89.6% and 91.1%, which were significant higher than those of PPD test and TBAb test ( P〈0.01 ) .Conclusion: T-SPOT.TB test has high sensibility and specificity in the diagnosis of smear negative pulmonary tuberculosis.It has important value in clinical.
出处 《中国医学创新》 CAS 2013年第31期124-125,共2页 Medical Innovation of China
关键词 菌阴结核 Γ干扰素释放试验 诊断 Tuberculosis Interferon-gamma release assay Diagnosis
  • 相关文献

参考文献10

二级参考文献47

  • 1张敦熔.耐药性的流行病学意义[J].中国防痨杂志,1997,4:155-155.
  • 2全国结核病流行病学抽样调查领导小组.1979全国结核病流行病学抽样调查综合简报[J].中国防痨通讯,1982,2:3-6.
  • 3中华人民共和国卫生部.1984/1985全国结核病流行病学抽样调查资料汇编[M].,-.18-19.
  • 4Yoon HJ,Song YG,Park WI,et al.Clinical manifestation and diagnosis of extrapulmonary tuberculosis[J].Yonsei Med J,2004,45(3):453-461.
  • 5Lalvani A,Pathan AA,McShane H,et al.Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells[J].Am J Respir Crit Care Med,2001,163(4):824-828.
  • 6World Health Organization.Global tuberculosis control,epidemiology,strategy,financing[M].Geneva:World Health Organization,2009:411.
  • 7Huang J,Shen M,Sun Y.Epidemiological analysis of extra-pulmonary tuberculosis in Shanghai[J].Zhonghua Jie He He Hu Xi Za Zhi,2000,23(10):606-608.
  • 8Sharma SK,Mohan A.Extrapulmonary tuberculosis[J].Indian J Med Res,2004,120(4):316-353.
  • 9Ozekinci T,Ozbek E,Celik Y.Comparison of tuberculin skin test and a specific T-cell-based test,T-Spot.TB,for the diagnosis of latent tuberculosis infection[J].J Int Med Res,2007,35(5):696-703.
  • 10Pai M,Riley LW,Colford JM.Interferon-gamma assays in the immunodiagnosis of tuberculosis:a systematic review[J].Lancet Infect Dis,2004,4(12):761-776.

共引文献1616

同被引文献154

引证文献10

二级引证文献74

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部