摘要
目的:评价γ干扰素释放结核感染T细胞斑点试验(T-SPOT.TB)检测在菌阴肺结核中的诊断价值。方法:将本院住院确诊菌阴肺结核67例患者作为观察组,同期入住的124例肺炎患者作为对照组,两组进行T-SPOT.TB、结核抗体、结核菌素试验(PPD)等检测。结果:T.SPOT.TB在菌阴肺结核组中的敏感性(89.6%)和特异性(91.1%)均高于对照组,比较差异均有统计学意义(P<0.01)。结论:T-SPOT.TB在诊断菌阴肺结核方面具有较高的敏感性和特异性,对菌阴肺结核有着重要的诊断价值。
Objective: To evaluate the diagnostic value of T-SPOT.TB in smear negative pulmonarytuberculosis.Method: Sixty-seven smear negative tuberculosis patients ( the observation group ) and 124 pneumonia patients ( the control group ) were enrolled in the test.The two groups were given γ-SPOT.TB, PPD and tuberculosis antibody ( TBAb ) test.Result: The sensibility and specificity of T-SPOT.TB test in observation group were 89.6% and 91.1%, which were significant higher than those of PPD test and TBAb test ( P〈0.01 ) .Conclusion: T-SPOT.TB test has high sensibility and specificity in the diagnosis of smear negative pulmonary tuberculosis.It has important value in clinical.
出处
《中国医学创新》
CAS
2013年第31期124-125,共2页
Medical Innovation of China
关键词
菌阴结核
Γ干扰素释放试验
诊断
Tuberculosis
Interferon-gamma release assay
Diagnosis