摘要
目的探讨双水平气道正压通气(BiPAP)呼吸机在治疗慢性阻塞性肺疾病急性加重期(AECOPD)合并Ⅱ型呼吸衰竭的临床疗效。方法将2010年1月至2011年12月收治的62例AECOPD合并Ⅱ型呼吸衰竭患者分为两组。治疗组42例患者予以BiPAP呼吸机加用抗感染、平喘、祛痰药物治疗;对照组20例患者只予以抗感染、平喘、祛痰等常规治疗。结果治疗组临床症状缓解率、血气分析指数改善情况均优于对照组,住院天数明显短于对照组;两组比较差异显著(P<0.05)。结论 BiPAP呼吸机在治疗AECOPD合并Ⅱ型呼吸衰竭安全、有效,但有效性与患者对BiPAP呼吸机依从性及医护人员的临床应用BiPAP呼吸机经验水平有一关系。
Objective To explore the clinical efficacy of application of of BiPAP ventilator in treatment of acute exacerbation of chronic obstructive pulmonary disease （AECOPD） complicated with type II respiratory failure. Methods A total of 62 patients with AECOPD complicat- ed with type II respiratory failure admitted during January 2010 to December 2011 were divided into 2 groups, 42 patients in trial group were trea- ted by BiPAP ventilator and anti - inflammatory, antiastbmatic and expectorant therapy, and 20 patients in control group were only treated with anti - inflammatory, antiasthmatic and expectorant therapy. Results The clinical symptoms of patients in trial group were relieved, their indices of blood gas analysis were also obviously improved, the duration of hospitalization days had also been significantly reduced ; and the difference be- tween these 2 groups was significant （ P 〈 0.05 ）. Conclusion The application of BiPAP ventilator in treatment of patients with acute exacerba- tion of chronic obstructive pulmonary disease （AECOPD） complicated with type 1 respiratory failure is safe and effective, but the efficacy is relat- ed to the compliance of patients to BiPAP breathing machine and level of experience of staffs in clinical application of BiPAP ventilator.
出处
《临床和实验医学杂志》
2013年第21期1748-1750,共3页
Journal of Clinical and Experimental Medicine
