摘要
目的总结质子泵抑制剂不良反应的规律和特点，为临床合理用药提供参考。方法检索CHKD全文数据库，对2008～2012年报道的质子泵抑制剂不良反应病伊进行统计分析。结果涉及质子泵抑制剂不良反应的文献30篇，报道例数34例；不良反应累及多个系统一器官，临床症状复杂多样，不良反应症状均比较严重，而且临床上属少见及罕见，经停药处理后预后较好。结论加强对该类药品不良反应的认识，注意防范，合理选用质子泵抑制剂。
Objective To summarize the regularity and characteristics of adverse drug reaction（ADR） induced by proton pump inhibitors, and provide reference for the ral;ional use of drugs in clinic. Methods Related literatures of ADR induced by proton pump inhibitors were collected from CHKD flail-text database during 2008 - 2012, then the included literatures were statistically analyzed. Results A total of 30 literatures relating to ADR induced by proton pump inhibitors were collected, including 34 cases. This group of ADR induced by proton pump inhibitors involved multiple system-organs, the clinical signs were 4;omplex and varied, and symptoms of adverse drug reactions were relatively serious, and rare in clinic, but prognosi was good after stopping drug treatment. Conclusion We should strengthen the understanding of these types of adcerse drug reactions, pay attention to the prevention and improve the rational use of proton pump inhibitors.
出处
《中国药物警戒》
2013年第11期683-686,共4页
Chinese Journal of Pharmacovigilance
关键词
质子泵抑制剂
药品不良反应
分析
proton pump inhibitors
adverse drug reaction
analysis
