摘要
目的:研究分析血浆同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)与不同分型分水岭脑梗死的相关性。方法:选择2010年1月到2013年6月汾西矿业集团总医院神经内科收治的分水岭脑梗死患者80例,经头颅MRI+DWI诊断为皮质前型、皮质后型、皮质下型及混合型各20例,以及无症状的正常人20例,分别测定血浆同型半胱氨酸及超敏C反应蛋白水平。结果:分水岭脑梗死患者血浆同型半胱氨酸水平显著高于正常人,差异有统计学意义(P<0.05);分水岭脑梗死患者血浆超敏C反应蛋白水平显著高于正常人,差异有统计学意义(P<0.05);皮质前型、皮质后型、皮质下型及混合型分水岭脑梗死患者血浆同型半胱氨酸水平及超敏C反应蛋白水平比较,差异无统计学意义。结论:不同分型的分水岭脑梗死的发生与血浆同型半胱氨酸及血浆超敏C反应蛋白水平有关,血浆同型半胱氨酸及血浆超敏C反应蛋白水平可作为预测及评价分水岭脑梗死的重要指标之一。
Objective： To study the correlation between plasma homocysteine（HCY） and hyper-sensitivity C-reac- tive protein （hs-CRP） related to different types of watershed cerebral infarction. Methods： 80 patients with watershed cerebral infarction during January 2010 to June 2013 admitted to the internal department of neurology were diagnosed by brain MRI ＋ DWI as cortical former type, the type cortex, subcortical and mixed type of the 20 cases, as well as a- symptomatic of the normal 20 cases. Plasma homocysteine and high-sensitivity C-reactive protein levels were measured for the patients. Results： The watershed cerebral infarction plasma homocysteine levels were significantly higher than normal people, and there was statistically significant difference （ P 〈 0.05 ） ; watershed infarction patients with high-sen- sitivity C-reactive protein levels were significantly higher than normal people, and also the difference was statistically sig- nificance （ P 〈 0.05 ） ; compared with plasma homocysteine levels and high-sensitivity C-reactive protein level of the pa- tients diagnosed as cortex former type, the type cortex, subcortical and mixed type, there was no statistically significant difference. Conclusions： Different types of watershed cerebral infarction is related to plasma homocysteine and plasma high-sensitivity C-reactive protein level, and plasma homocysteine and plasma high-sensitivity C-reactive protein levels can be regarded as a predictor of cerebral infarction and evaluation of watershed important indicators.
出处
《山西职工医学院学报》
CAS
2013年第5期14-16,共3页
Journal of Shanxi Medical College for Continuing Education
关键词
同型半胱氨酸
超敏C反应蛋白
分水岭脑梗死
相关性
Homocysteine
hypersensitivity C-reactive protein（hs-CRP）
watershed infarction（WI）
correlation
