摘要
目的 :观察香砂六君丸治疗脾胃虚弱型糖尿病胃轻瘫(Diabetic Gastroparesis,DGP)的临床疗效。方法 :将60例脾胃虚弱型糖尿病胃轻瘫患者随机分为治疗组和对照组,各30例。在降糖药物控制血糖的基础上,治疗组予香砂六君丸每日3次,每次8粒,对照组予多潘立酮片口服10 mg/次,每日3次,于餐前30 min口服,用药疗程均为4周。观察两组患者的疗效以及治疗前后主要症状、中医证候积分、胃排空率。结果 :治疗组总有效率(93.34%)明显优于对照组总有效率(73.3%),差异具有统计学意义(P<0.05);两组治疗后餐后饱胀、食欲减退、嗳气、中医证候积分均有所改善,与治疗前比较差异有统计学意义(P<0.05);治疗组治疗后与对照组比较,饱胀、食欲减退、嗳气、中医证候积分差异有统计学意义(P<0.01)。两组患者用药前后血糖、肝肾功能均无异常,也未见不良反应发生。结论:香砂六君丸可以有效改善脾胃虚弱型糖尿病胃轻瘫患者临床症状,促进患者胃排空率。
Objective： To observe the clinical effect of Xiangsha Liujunzi Pill on treating diabetic gastroparesis due to the weakness of spleen and stomach. Methods： A randomized controlled clinical trial was carried out. Sixty patients were randomly divided into control group and treatment group. The treatment group （ n=30 ） were given Xiangsha Liujunzi Pill, three times a day ; the control group （ n=30 ） was treated with Domperidone orally 10 mg per day, three times a day. The clinical effect and changes of syndrome score of traditional Chinese medicine and gastric emptying rate were observed before and after treatment. Results ： The total effective rate in treatment group （ 93.34% ）was higher than that in control group （ 73.3%, P〈0.05 ）. Syndrome score of traditional Chinese medicine after treatment was decreased as compared with those before treatment in two groups （ P〈0.05 ）. Conclusion ： Xiangsha Liujunzi Pill can improve symptoms status of diabetic gastroparesis with weakness of spleen and stomach, enhance gastric emptying rate and has no adverse effect.
出处
《辽宁中医药大学学报》
CAS
2013年第12期137-139,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
第二批江苏省优秀中青年中医临床人才研修专项课题(YX1215)
关键词
香砂六君丸
脾胃虚弱型
糖尿病胃轻瘫
Xiangsha Liujunzi Pill
weakness of spleen and stomach
diabetic gastroparesis
