摘要
目的：分析我院住院患者抗菌药的应用情况及趋势，为合理使用抗菌药提供依据。方法：回顾性收集我院2010—2012年出院患者抗茵药的使用记录，以限定El剂量（DDD）为单位，计算抗茵药使用强度（AUD）并进行分析。结果：我院抗茵药使用强度3年来呈下降趋势，由2010年的68．63DDD／100人天下降到2012年的42．6lDDD／100人天，尤以手术科室下降明显。头孢菌素类复方制剂、第三代头孢菌素始终位居前3位，喹诺酮类抗茵药使用强度下降明显。结论：我院存在用药过度、用药集中等问题。应严格限制头孢菌素类复方制剂、第三代头孢菌素临床应用，提高合理用药水平。
Objective： To provide an evidence for rational clinical use of antibacterials through analysis of the ap- plication and trend of antibacterials in the inpatients of our hospital. Methods ： By retrospective study, the data of drug used during 2010-2012 were collected and analyzed. With the defined daily dose（DDD） as the .unit,antibacterial use density （AUD） was calculated and its analysis Was made . Results：The AUD in our hospital markedly decreased from 68.63 DDD / 100 persons/d in 2010 to 42.61 DDD/100 persons/d in 2012 in the past 3 year, especially in the surgical departments. Cephalosporins compound preparation and third generation cephalosporins always ranked in the first three places. But quin- olones significantly decreased. Conclusion： Antimicrobial drug use in the clinic in our hospital might have such problems as overmedication, dense medication. Cephalosporins compound preparation and third generation eephalosporins should be strictly restricted in clinical appligation in order to improve the rational use of drugs.
出处
《药物流行病学杂志》
CAS
2013年第11期609-612,共4页
Chinese Journal of Pharmacoepidemiology
关键词
抗菌药
限定日剂量
使用强度
药物利用
Antibacterials
Defined daily dose
Antibiotics use density
Drug utilization
