摘要
采用循环伏安法(CV)和差分脉冲伏安法(DPV),研究了卡铂在多壁碳纳米管玻碳电极(MWCNTs/GCE)上的电化学行为并建立了卡铂的测定方法。结果表明:卡铂在多壁碳纳米管玻碳电极上有一对氧化还原峰,氧化峰电位Epa与还原峰电位Epc分别为0.73 V、0.26 V,峰电位之差为?E=0.47 V,Ipa/Ipc=1.57。在优化条件下,卡铂的氧化峰电流与其浓度在0.22～0.67 mmol/L范围内成良好的线性关系(r=0.9942),检出限为0.2 mmol/L。方法操作简便,准确可靠、灵敏度高,可用于卡铂含量的直接测定。
The electrochemical behavior of carboplatin at multi-walled carbon nanotubes modified glassy carbon electrode was investigated by cyclic voltammetry and differential pulse voltammetry, and a new method was established for the determination of carboplatin. The results show that one pair of redox peaks of carboplatin with 0.73 V of Epa and 0.26 V of Epc （△E=0.47 V, and Ip/Ipc=1.57） was obtained at multi-walled carbon nanotubes modified glassy carbon electrode by cyclic voltammetry. Under the optimal conditions, the oxidization peak was linearly related to the concentration of carboplatin in the range of 0.22-0.67 mmol/L with the detection limit of 0.2 mmol/L. The method was convenient, accurate, credible and sensitive, and can be used in the determination of carboplatin.
出处
《贵金属》
CAS
CSCD
北大核心
2013年第4期48-52,共5页
Precious Metals
基金
云南省创新团队计划(2011HC008)
云南省高校科技创新团队计划项目(2011UY09)
关键词
分析化学
卡铂
多壁碳纳米管
电极
电化学行为
伏安法
analytical chemistry
carboplatin
multi-walled carbon nanotubes
electrode
electrochemical behavior
voltammetry
