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Treatments of disease relapse after allogeneic stem cell transplantation focusing on donor lymphocyte infusion

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摘要 Hematopoietic stem cell transplantation (SCT) is a potentially curative treatment for patients with hematologic malignancies, such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). There has been tremendous progress in the past several decades in allogeneic SCT with better outcomes through improvements in supportive care, expansion of stem cell donor options (HLA-matched unrelated donors (MUD), haploidentical related donors, and cord blood units (CBUs) etc.), and introduction of better tolerated reduced intensity conditioning (RIC) regimens. Hematopoietic stem cell transplantation (SCT) is a potentially curative treatment for patients with hematologic malignancies, such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). There has been tremendous progress in the past several decades in allogeneic SCT with better outcomes through improvements in supportive care, expansion of stem cell donor options (HLA-matched unrelated donors (MUD), haploidentical related donors, and cord blood units (CBUs) etc.), and introduction of better tolerated reduced intensity conditioning (RIC) regimens.
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2013年第22期4380-4388,共9页 中华医学杂志(英文版)
关键词 donor lymphocyte infusion acute myeloid leukemia allogeneic stem cell transplantation graft versus leukemia effect graft versus host disease donor lymphocyte infusion, acute myeloid leukemia, allogeneic stem cell transplantation, graft versus leukemia effect, graft versus host disease
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