摘要
目的:观察静脉注射冻干重组人脑利钠肽(rhBNP)在治疗老老年慢性心力衰竭(CHF)的临床效果及安全性。方法:38例老老年冠心病CHF患者,使用rhBNP治疗,比较用药前后血压、心率、尿量、呼吸困难程度、血清肌酐、左室射血分数及血浆脑利钠肽(BNP)等的变化。结果:使用rhBNP治疗后老老年CHF患者症状改善,同时左室射血分数提高,血浆BNP水平明显下降。结论:利用静脉注射冻干重组人脑利钠肽治疗老老年CHF,安全可靠。
Objective：To observe the efficacy and safety of domestic Recombinant human brain natriuretic peptide（rhBNP） for treating in the elderly patients with heart failure. Methods： 38 patients with the elderly with heart failure. The patients received rhBNP.The changes in BP,HR,SCr,left ventricular ejection fraction（LVEF） and BNP were compared before and after treatment. Results：The dyspnea and symptoms in the elderly patients with heart failure can be improved by rhBNP, LVEF in patients were improved,the levels of BNP were significant degraded.Conclusion： rhBNP is effective in treating the elderly patients with heart failure, The safety of rhBNP is reliable.
出处
《中国医药导刊》
2013年第11期1844-1845,共2页
Chinese Journal of Medicinal Guide
关键词
心力衰竭
老老年人
rhBNP
rhBNP
Heart failure
The elderly
